SCHEMBL12439797

SCHEMBL12439797

N/C(=N\O)c1cc(-c2cc(F)ccc2C(F)(F)F)ccn1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 7/20 0.44
TRPA1 O75762 2/20 0.43
KDM1A O60341 1/20 0.39
CYP2C9 P11712 2/20 0.38
SCN5A Q14524 1/20 0.38
SCN10A Q9Y5Y9 2/20 0.35
GAA P10253 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
AR P10275 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AAK1 Q2M2I8 2/20 0.32
CYP11B2 P19099 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1935777 1.00 SCN9A (0.44) SCN9ATRPA1KDM1ACYP2C9SCN5A
SCHEMBL12439786 0.89 TRPA1 (0.43) SCN9ATRPA1KDM1ASCN10AGAA
SCHEMBL1935000 0.89 TRPA1 (0.43) SCN9ATRPA1KDM1ASCN10AGAA
SCHEMBL1935109 0.88 SCN9A (0.49) SCN9ACYP2C9SCN5ASCN10AGAA
SCHEMBL12514481 0.88 SCN9A (0.49) SCN9ACYP2C9SCN5ASCN10AGAA
SCHEMBL12439817 0.87 SCN9A (0.38) SCN9ATRPA1CYP2C9SCN5ASCN10A
SCHEMBL12439746 0.85 SCN9A (0.48) SCN9ATRPA1SCN10AGAANPC1
SCHEMBL1934839 0.85 SCN9A (0.48) SCN9ATRPA1SCN10AGAANPC1
SCHEMBL1935230 0.84 GAA (0.40) SCN9ACYP2C9SCN5ASCN10AGAA
SCHEMBL12439827 0.84 GAA (0.40) SCN9ACYP2C9SCN5ASCN10AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2332936-B1 PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2013-09-04 EP disclosed
US-20110178132-A1 PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-07-21 US disclosed
US-20110178132-A1 PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-07-21 US disclosed
EP-2332936-A1 PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2011-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178132-A1 PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL C5, PRDX1, PRDX4 SCN9A 3140/4885TRPA1 324/4885KDM1A 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.