SCHEMBL12440225

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2326924	0.86	CNR2 (0.45)	HTTSMOSMN1; SMN2TUBB4ATUBB
	SCHEMBL2330119	0.83	MET (0.47)	GPR119ALOX5APFEN1
	SCHEMBL12440312	0.81	GBA1 (0.45)	GPR119ALOX5APFEN1
	SCHEMBL12440268	0.79	CNR2 (0.41)	HTTMAPTSMN1; SMN2KCNH2CNR2
	SCHEMBL19791547	0.78	LMNA (0.38)	HTTSMN1; SMN2TUBB4ATUBBTUBA3C
	SCHEMBL29891810	0.77	HTT (0.64)	GPR119HTTSMN1; SMN2TUBB4ATUBB
	SCHEMBL12580536	0.77	HTT (0.64)	GPR119HTTSMN1; SMN2TUBB4ATUBB
	SCHEMBL2321632	0.76	MET (0.47)	GPR119
	SCHEMBL13978015	0.76	MET (0.46)	GPR119ALOX5APFEN1
	SCHEMBL12440231	0.74	GPR119 (0.50)	GPR119HTTSMOMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.