SCHEMBL12440274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12441219	0.93	ACHE (0.44)	ACHETGFBR1KDRFLT1ACVR1
	SCHEMBL12440257	0.89	TNIK (0.42)	LRRK2KDRFLT1FLT4
	SCHEMBL19791572	0.87	KDR (0.39)	KDRFLT1FLT4
	SCHEMBL12440260	0.85	WNT1 (0.46)	FLT3
	SCHEMBL2321729	0.85	MAPK1 (0.42)	KDRFLT1FLT4MKNK1
	SCHEMBL15460613	0.84	HCAR2 (0.40)	—
	SCHEMBL19791324	0.83	MAPK1 (0.39)	KDRFLT1FLT4MKNK1
	SCHEMBL2327048	0.82	FLT3 (0.44)	FLT3KDRFLT1FLT4
	SCHEMBL246289	0.82	GRM4 (0.45)	ACHENPC1RAB9AFLT3KDR
	SCHEMBL12440280	0.81	MCHR1 (0.40)	ACHEKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.