SCHEMBL12440260

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12441219	0.93	ACHE (0.44)	WNT1LTA4HCLK2CLK3DYRK1A
	SCHEMBL13834517	0.88	SLC6A3 (0.38)	WNT1DYRK1AAVPR1B
	SCHEMBL13834312	0.87	RPS6KA3 (0.43)	BACE1CLK2CLK3DYRK1AMAP4K4
	SCHEMBL12440256	0.86	WNT1 (0.44)	WNT1LTA4HBACE1CLK2CLK3
	SCHEMBL12440274	0.85	ACHE (0.46)	FLT3
	SCHEMBL19791373	0.84	ABCG2 (0.39)	WNT1BACE1MAP4K4CHRNB2CHRNA4
	SCHEMBL12440280	0.84	MCHR1 (0.40)	LTA4HAVPR1BHRH3
	SCHEMBL19791573	0.83	ACP1 (0.41)	WNT1LTA4HDYRK1AAVPR1BHRH3
	SCHEMBL2320748	0.83	MET (0.40)	WNT1DYRK1AMAPK1
	SCHEMBL19791445	0.83	MCHR1 (0.42)	HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.