Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12793969 | 0.97 | PDK2 (0.36) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL2606535 | 0.95 | PDK2 (0.35) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL20036912 | 0.95 | PDK2 (0.38) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL14073273 | 0.95 | ALDH1A1 (0.37) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL24527187 | 0.95 | PDK2 (0.36) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL15178611 | 0.92 | PDK2 (0.39) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL10010140 | 0.92 | PDK2 (0.37) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL24646511 | 0.92 | PDK2 (0.39) | PDK2HTTNPSR1L3MBTL1CYP2A6 | |
| SCHEMBL15801394 | 0.92 | KDM4E (0.30) | PDK2HTTNPSR1L3MBTL1 | |
| SCHEMBL24252007 | 0.91 | PDK2 (0.40) | PDK2HTTNPSR1L3MBTL1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190237675-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10312452-B2 | Aromatic amine derivative and organic electroluminescence device utilizing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| EP-1883688-B1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-11 | — | — | EP | disclosed |
| US-9461249-B2 | Compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-9461249-B2 | Compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-20140239283-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-08-28 | — | — | US | disclosed |
| US-20140239283-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-08-28 | — | — | US | disclosed |
| EP-1860097-B1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-20090066225-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090066225-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | TYR, DDT, PAH | PDK2 519/4885HTT 1295/4885NPSR1 2306/4885 |
| US-10312452-B2 | Aromatic amine derivative and organic electroluminescence device utilizing the same | TYR, OCIAD2, MAOA | PDK2 617/4885HTT 1607/4885NPSR1 4667/4885 |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | TYR, TOE1, GPX1 | PDK2 1138/4885HTT 1570/4885NPSR1 2907/4885 |
| US-20090066225-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | TYR, NLRP1, NLRP3 | PDK2 953/4885HTT 1154/4885NPSR1 4092/4885 |
| US-20190237675-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | TYR, NLRP1, NLRP3 | PDK2 953/4885HTT 1154/4885NPSR1 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.