SCHEMBL1244094

SCHEMBL1244094

O=C(c1ccc(I)cc1)c1ccc(I)cc1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.65
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
SRD5A2 P31213 5/20 0.55
LMNA P02545 2/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
HTT P42858 2/20 0.55
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
PKM P14618 1/20 0.55
GSK3B P49841 1/20 0.54
ALDH1A1 P00352 3/20 0.52
ITGA1 P56199 1/20 0.48
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9389844 1.00 TPMT (0.65) TPMTCA1CA2SRD5A2LMNA
SCHEMBL3841301 1.00 TPMT (0.65) TPMTCA1CA2SRD5A2LMNA
SCHEMBL9388483 0.92 TPMT (0.56) TPMTCA1CA2SRD5A2LMNA
SCHEMBL3468575 0.89 HTT (0.75) TPMTCA1CA2SRD5A2LMNA
SCHEMBL2479840 0.89 ALDH1A1 (0.70) TPMTCA1CA2SRD5A2LMNA
SCHEMBL24787903 0.87 TPMT (0.52) TPMTCA1CA2SRD5A2LMNA
SCHEMBL10075868 0.87 ALDH1A1 (0.76) TPMTCA1CA2SRD5A2LMNA
SCHEMBL8143209 0.87 LMNA (0.59) TPMTCA1CA2SRD5A2LMNA
SCHEMBL851491 0.87 SRD5A2 (0.64) TPMTCA1CA2SRD5A2HPGD
SCHEMBL9850489 0.87 TPMT (0.52) TPMTCA1CA2SRD5A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479063-B Polyarylether nitrile containing naphthalene structure and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN claimed
CN-114479062-A Polyaryletherketone containing naphthalene structure and preparation method thereof 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-114479063-A Poly (arylene ether nitrile) containing naphthalene structure and preparation method and application thereof 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-111592450-A Thermal induced delayed fluorescent material based on anthrone acceptor and preparation method thereof 电子科技大学 2020-08-28 CN claimed
CN-107722274-A A kind of preparation method of melt-blown polyphenylene sulfide 天津工业大学 2018-02-23 CN claimed
CN-100343256-C Biaryl substituted diazabicycloalkane amides as nicotinic acetylcholine agonists ASTRAZENECA AB (SE) 2007-10-17 CN claimed
CN-1678615-A Biaryl substituted diazabicycloalkanes as nicotinic acetylcholine antagonists ASTRAZENECA AB (SE) 2005-10-05 CN claimed
CN-1675215-A Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists ASTRAZENECA AB (SE) 2005-09-28 CN claimed
EP-0502993-B1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING A DECREASED AMOUNT OF DISULFIDE RADICALS EASTMAN CHEM CO (US) 1995-06-07 EP claimed
EP-0530703-A2 Method for the preparation of polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
US-5155183-A Heating with iodine-terminated polyphenylene sulfide in melt p hase EASTMAN KODAK COMPANY (US) 1992-10-13 US claimed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
EP-0502993-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING A DECREASED AMOUNT OF DISULFIDE RADICALS. EASTMAN KODAK CO (US) 1992-09-16 EP claimed
US-5097003-A Reacting dihalogen compound with alkali meal sulfide not deprived of free water at low temperatures TOSOH CORPORATION (JP) 1992-03-17 US claimed
WO-1991009072-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING AN INCREASED AMOUNT OF DISULFIDE RADICALS EASTMAN KODAK COMPANY (US) 1991-06-27 WO claimed
WO-1991008249-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING A DECREASED AMOUNT OF DISULFIDE RADICALS EASTMAN KODAK COMPANY (US) 1991-06-13 WO claimed
US-4977224-A Process for the preparation of copoly(arylene sulfide) having a decreased amount of disulfide radicals EASTMAN KODAK COMPANY (US) 1990-12-11 US claimed
EP-0399921-A1 Process for the preparation of low color copoly(arylene sulfide) EASTMAN KODAK COMPANY (US) 1990-11-28 EP claimed
US-4945155-A Preparation of low color copoly(arylene sulfide) by heating copoly(arylene sulfide) EASTMAN KODAK COMPANY (US) 1990-07-31 US claimed
EP-0346085-A2 Process for producing polyphenylene sulfide ketone polymers Tosoh Corporation (JP) 1989-12-13 EP claimed