SCHEMBL12440955

SCHEMBL12440955

Cc1cccc(Br)c1OCc1cccc(Br)c1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 14/20 0.56
ESR1 P03372 1/20 0.51
NR3C1 P04150 1/20 0.51
PGR P06401 1/20 0.51
NR3C2 P08235 1/20 0.51
AR P10275 1/20 0.51
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
MAOA P21397 5/20 0.46
PARP15 Q460N3 1/20 0.44
PARP14 Q460N5 1/20 0.44
PARP10 Q53GL7 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12772155 0.85 HTR1A (0.50) MAOBTHRATHRBALDH1A1SMN1; SMN2
SCHEMBL12440978 0.84 THRA (0.56) MAOBESR1NR3C1PGRNR3C2
SCHEMBL9893995 0.83 MAOB (0.51) MAOBESR1NR3C1PGRNR3C2
SCHEMBL12440973 0.83 MAOB (0.56) MAOBIDO1AGXTSMN1; SMN2
SCHEMBL5668021 0.81 MAOB (0.57) MAOBESR1NR3C1PGRNR3C2
SCHEMBL12514199 0.81 MAOB (0.53) MAOBESR1NR3C1PGRNR3C2
SCHEMBL9946036 0.81 ESR1 (0.49) MAOBESR1NR3C1PGRNR3C2
SCHEMBL13429926 0.81 MAOB (0.56) MAOBESR1NR3C1PGRNR3C2
SCHEMBL13429686 0.80 MAOB (0.52) MAOBESR1NR3C1PGRNR3C2
SCHEMBL5666233 0.79 MAOB (0.54) MAOBESR1NR3C1PGRNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MAOB 2353/4885ESR1 67/4885NR3C1 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.