SCHEMBL12440978

SCHEMBL12440978

Cc1cc(C)c(OCc2cccc(Br)c2)c(Br)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.56
THRB P10828 2/20 0.56
ESR1 P03372 1/20 0.56
NR3C1 P04150 1/20 0.56
PGR P06401 1/20 0.56
NR3C2 P08235 1/20 0.56
AR P10275 1/20 0.56
MAOB P27338 11/20 0.54
MAPT P10636 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
IDO1 P14902 2/20 0.47
AGXT P21549 2/20 0.47
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
LMNA P02545 2/20 0.46
MAOA P21397 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12440971 0.86 MEN1 (0.55) THRATHRBESR1NR3C1PGR
SCHEMBL13429949 0.85 MAOB (0.51) THRATHRBESR1NR3C1PGR
SCHEMBL12440957 0.85 THRA (0.59) THRATHRBESR1NR3C1PGR
SCHEMBL12440963 0.85 MAOB (0.51) THRATHRBMAOBMAPTL3MBTL1
SCHEMBL12440955 0.84 MAOB (0.56) THRATHRBESR1NR3C1PGR
SCHEMBL12440977 0.84 MAOB (0.55) THRATHRBMAOBMAPTL3MBTL1
SCHEMBL12514355 0.84 THRA (0.52) THRATHRBESR1NR3C1PGR
SCHEMBL13429708 0.83 MAOB (0.49) THRATHRBESR1NR3C1PGR
SCHEMBL9893695 0.83 THRA (0.51) THRATHRBESR1NR3C1PGR
SCHEMBL9946069 0.81 THRA (0.49) THRATHRBESR1NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 THRA 3000/4885THRB 3991/4885ESR1 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.