SCHEMBL12440959

SCHEMBL12440959

Cc1cc(C)c(OCc2ccccc2Cl)c(Br)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
LMNA P02545 2/20 0.48
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
KDM4E B2RXH2 2/20 0.41
IDO1 P14902 2/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12030992 0.89 IDO1 (0.47) MAPTL3MBTL1THRATHRBCYP1A2
SCHEMBL13429869 0.86 CYP1A2 (0.45) MAPTTHRATHRBLMNACYP1A2
SCHEMBL9893400 0.83 CYP1A2 (0.46) MAPTL3MBTL1THRATHRBLMNA
SCHEMBL13429699 0.83 CYP1A2 (0.46) MAPTL3MBTL1THRATHRBCYP1A2
SCHEMBL12440961 0.82 MAPT (0.50) MAPTL3MBTL1THRATHRBLMNA
SCHEMBL2292139 0.80 THRA (0.48) MAPTL3MBTL1THRATHRBLMNA
SCHEMBL12440971 0.78 MEN1 (0.55) MAPTL3MBTL1THRATHRBLMNA
SCHEMBL13743527 0.78 KMT2A (0.52) MAPTL3MBTL1LMNACYP3A4CYP2C19
SCHEMBL12440960 0.76 THRA (0.51) MAPTL3MBTL1THRATHRBLMNA
SCHEMBL12432412 0.76 HTR1A (0.54) MAPTL3MBTL1LMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MAPT 456/4885L3MBTL1 4308/4885THRA 3000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.