SCHEMBL12440971

SCHEMBL12440971

Cc1cc(C)c(OCc2ccccc2)c(Br)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 7/20 0.55
L3MBTL1 Q9Y468 4/20 0.55
THRB P10828 6/20 0.54
THRA P10827 5/20 0.54
LMNA P02545 3/20 0.52
GAA P10253 3/20 0.47
HPGD P15428 1/20 0.47
KDM4E B2RXH2 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
MAOB P27338 1/20 0.44
MAPK1 P28482 2/20 0.43
BLM P54132 1/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1502370 0.91 THRB (0.58) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL10481838 0.88 MAPT (0.50) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL12440978 0.86 THRA (0.56) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL13508899 0.84 THRB (0.46) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL13429977 0.84 THRB (0.48) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL12440965 0.84 MAPT (0.49) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL12440960 0.84 THRA (0.51) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL12440963 0.83 MAOB (0.51) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL12440957 0.83 THRA (0.59) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL12514358 0.83 THRA (0.50) MEN1KMT2APOLBMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 US disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MEN1 1758/4885KMT2A 1122/4885POLB 3997/4885
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 MEN1 609/4885KMT2A 3209/4885POLB 1470/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 MEN1 609/4885KMT2A 3209/4885POLB 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.