SCHEMBL1244527

SCHEMBL1244527

O=P(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
ALDH1A1 P00352 3/20 0.45
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA5A P35218 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ESR1 P03372 1/20 0.41
NFE2L2 Q16236 1/20 0.41
POLB P06746 3/20 0.40
HPGD P15428 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX12 P18054 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10635216 1.00 LMNA (0.50) LMNANPC1RAB9AALDH1A1CA2
Hydrogen Peroxide SCHEMBL8672190 0.90 BCL2L1 (0.46) LMNANPC1RAB9AALDH1A1CA2
Hydrogen Peroxide SCHEMBL8672187 0.90 BCL2L1 (0.46) LMNANPC1RAB9AALDH1A1CA2
SCHEMBL9927352 0.89 CES2 (0.39) LMNANPC1RAB9AALDH1A1CA2
SCHEMBL779999 0.89 CES2 (0.39) LMNANPC1RAB9AALDH1A1CA2
SCHEMBL19010398 0.89 ACHE (0.52) LMNANPC1RAB9AALDH1A1MEN1
SCHEMBL132983 0.87 LMNA (0.60) LMNAALDH1A1CA2CA4CA5A
SCHEMBL5436616 0.87 LMNA (0.60) LMNAALDH1A1CA2CA4CA5A
SCHEMBL5439069 0.87 LMNA (0.60) LMNAALDH1A1CA2CA4CA5A
SCHEMBL4791094 0.86 MEN1 (0.50) LMNANPC1RAB9AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12615908-B2 Wide bandgap perovskite quantum dots in a perovskite matrix and process for preparing same Huawei Technologies Canada Co., Ltd. (CA) 2026-04-28 US claimed
CN-119285931-A Preparation method of polyarylether phosphine oxide intrinsic type room temperature phosphorescent material 重庆理工大学 2025-01-10 CN claimed
CN-114702949-B Perovskite quantum dot-polymer composite film and preparation method thereof 中国矿业大学 2024-02-27 CN claimed
CN-113336936-B Sulfonated aromatic phosphine oxide polymer containing bisphenol fluorene, and preparation method and application thereof 上海应用技术大学 2023-08-29 CN claimed
WO-2023087117-A1 WIDE BANDGAP PEROVSKITE QUANTUM DOTS IN A PEROVSKITE MATRIX AND PROCESS FOR PREPARING SAME Huawei Technologies Canada Co., Ltd. (CA) 2023-05-25 WO claimed
US-20230165129-A1 WIDE BANDGAP PEROVSKITE QUANTUM DOTS IN A PEROVSKITE MATRIX AND PROCESS FOR PREPARING SAME Huawei Technologies Canada Co., Ltd. (CA) 2023-05-25 US claimed
CN-115819258-A Preparation method of sitagliptin intermediate by using phosphine-oxygen double bond-containing catalyst 浙江大学 2023-03-21 CN claimed
CN-114702949-A Perovskite quantum dot-polymer composite film and preparation method thereof 中国矿业大学 2022-07-05 CN claimed
CN-108948353-B Preparation method of atomic oxygen resistant polyimide material 义乌市诠铈新材料有限公司 2020-12-04 CN claimed
US-20200131436-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE CHROMOPHORES AND ORGANIC LAYERS INCLUDING THE SAME WRIGHT STATE UNIVERSITY (US) 2020-04-30 US claimed
US-20080233455-A1 Proton conductors based on aromatic polyethers and their use as electolytes in high temperature pem fuel cells ADVENT TECHNOLOGIES SA (GR) 2008-09-25 US claimed
WO-2008090412-A2 PROTON CONDUCTING AROMATIC POLYETHER POLYMERS WITH PYRIDINYL SIDE CHAINS FOR FUEL CELLS ADVENT TECHNOLOGIES (GR) 2008-07-31 WO claimed
US-20080160378-A1 Novel poly(arylene ether) copolymers containing pyridine units as proton exchange membranes ADVENT TECHNOLOGIES SA (GR) 2008-07-03 US claimed
US-20080113227-A1 Development and characterization of novel proton conducting aromatic polyether type copolymers bearing main and side chain pyridine groups ADVENT TECHNOLOGIES 2008-05-15 US claimed
US-20080070093-A1 Development and characterization of novel proton conducting aromatic polyether type copolymers bearing main and side chain pyridine groups ADVENT TECHNOLOGIES (GR) 2008-03-20 US claimed
WO-2007084759-A2 CHLORINE RESISTANT DESALINATION MEMBRANES BASED ON DIRECTLY SULFONATED POLY(ARYLENE ETHER SULFONE) COPOLYMERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-07-26 WO claimed
US-20070163951-A1 Chlorine resistant desalination membranes based on directly sulfonated poly(Arylene Ether Sulfone) copolymers NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA 2007-07-19 US claimed
WO-2000024818-A1 CYCLIC OLIGOMER NANOCOMPOSITES TRITON SYSTEMS, INC. (US) 2000-05-04 WO claimed
US-5691442-A RADIATION TRANSPARENT POLYMERS WITH PHENOL ENDCAPPING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-11-25 US claimed
US-5079333-A Novel mine-terminated poly(arylene ether phosphine oxide) oligomer VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1992-01-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080070093-A1 Development and characterization of novel proton conducting aromatic polyether type copolymers bearing main and side chain pyridine groups PAH, PARG, PAM LMNA 1525/4885NPC1 4874/4885RAB9A 1959/4885
US-12615908-B2 Wide bandgap perovskite quantum dots in a perovskite matrix and process for preparing same KCNQ2, KCNQ1, KCNQ4 LMNA 2924/4885NPC1 3880/4885RAB9A 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.