SCHEMBL12445338

SCHEMBL12445338

O=C(O)c1ccc2c(c1)OCCOCCOCCOCCOCCO2

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.72
MAPT P10636 3/20 0.71
NPSR1 Q6W5P4 1/20 0.71
ALDH1A1 P00352 3/20 0.70
MAPK1 P28482 2/20 0.70
TSHR P16473 2/20 0.62
STAT3 P40763 1/20 0.59
PKM P14618 2/20 0.58
LMNA P02545 1/20 0.58
KMT2A Q03164 1/20 0.58
SRD5A2 P31213 1/20 0.57
ATM Q13315 1/20 0.57
CTNNB1 P35222 1/20 0.57
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NFKB1 P19838 1/20 0.55
MAOB P27338 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2807412 1.00 KDM4E (0.72) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL22292225 1.00 KDM4E (0.72) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL29363947 1.00 KDM4E (0.72) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL16784086 1.00 KDM4E (0.72) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL16784085 1.00 KDM4E (0.72) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL10031399 1.00 KDM4E (0.72) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL2806009 1.00 KDM4E (0.72) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL16784084 0.95 KDM4E (0.66) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL619634 0.94 MAPK1 (0.78) KDM4EMAPTNPSR1ALDH1A1MAPK1
SCHEMBL16784083 0.91 ALDH1A1 (0.64) KDM4EMAPTNPSR1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9988466-B2 Benzocrown ether graft polymer with lithium isotopic separation effect and preparation method thereof TIANJIN POLYTECHNIC UNIVERSITY (CN) 2018-06-05 US disclosed
EP-2537854-B1 METHOD FOR PRODUCING 18F-LABELED COMPOUND AND HIGH MOLECULAR COMPOUND TO BE USED IN THE METHOD TOKYO INST TECH (JP) 2016-12-14 EP disclosed
US-9257651-B2 Organic electroluminescence element and method for manufacturing organic electroluminescence element KONICA MINOLTA HOLDINGS, INC. (JP) 2016-02-09 US disclosed
US-9073802-B2 Method for producing 18F-labeled compound and high molecular compound to be used in the method TOKYO INSTITUTE OF TECHNOLOGY (JP) 2015-07-07 US disclosed
US-9073802-B2 Method for producing 18F-labeled compound and high molecular compound to be used in the method TOKYO INSTITUTE OF TECHNOLOGY (JP) 2015-07-07 US disclosed
US-20150152201-A1 BENZOCROWN ETHER GRAFT POLYMER WITH LITHIUM ISOTOPIC SEPARATION EFFECT AND PREPARATION METHOD THEREOF TIANJIN POLYTECHNIC UNIVERSITY (CN) 2015-06-04 US disclosed
US-20130087778-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENCE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-11 US disclosed
US-20130087778-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENCE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-11 US disclosed
US-20120329968-A1 METHOD FOR PRODUCING 18F-LABELED COMPOUND AND HIGH MOLECULAR COMPOUND TO BE USED IN THE METHOD NIIGATA UNIVERSITY (JP) 2012-12-27 US disclosed
US-20120329968-A1 METHOD FOR PRODUCING 18F-LABELED COMPOUND AND HIGH MOLECULAR COMPOUND TO BE USED IN THE METHOD NIIGATA UNIVERSITY (JP) 2012-12-27 US disclosed
US-7717550-B2 Preservative solution BROTHER KOGYO KABUSHIKI KAISHA (JP) 2010-05-18 US disclosed
US-7717550-B2 Preservative solution BROTHER KOGYO KABUSHIKI KAISHA (JP) 2010-05-18 US disclosed
US-7683025-B2 Synthesis and self-assembly of ABC triblock bola peptide amphiphiles NORTHWESTERN UNIVERSITY (US) 2010-03-23 US disclosed
US-7683025-B2 Synthesis and self-assembly of ABC triblock bola peptide amphiphiles NORTHWESTERN UNIVERSITY (US) 2010-03-23 US disclosed
US-7377973-B2 Water-based ink for ink-jet recording BROTHER KOGYO KABUSHIKI KAISHA (JP) 2008-05-27 US disclosed
US-7377973-B2 Water-based ink for ink-jet recording BROTHER KOGYO KABUSHIKI KAISHA (JP) 2008-05-27 US disclosed
US-20070153072-A1 WATER-BASED INK FOR INK-JET RECORDING BROTHER KOGYO KABUSHIKI KAISHA (JP) 2007-07-05 US disclosed
US-20070153072-A1 WATER-BASED INK FOR INK-JET RECORDING BROTHER KOGYO KABUSHIKI KAISHA (JP) 2007-07-05 US disclosed
US-20070137519-A1 Preservative Solution BROTHER KOGYO KABUSHIKI KAISHA (JP) 2007-06-21 US disclosed
US-20070137519-A1 Preservative Solution BROTHER KOGYO KABUSHIKI KAISHA (JP) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120329968-A1 METHOD FOR PRODUCING 18F-LABELED COMPOUND AND HIGH MOLECULAR COMPOUND TO BE USED IN THE METHOD FOS, FOSB, FGFR1 KDM4E 2494/4885MAPT 1952/4885NPSR1 850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.