Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854874 | 0.87 | STAT3 (0.55) | STAT3STAT1PDE2APDE10AHDAC6 | |
| SCHEMBL4745594 | 0.81 | STAT3 (0.52) | STAT3STAT1HDAC6HDAC3HDAC4 | |
| SCHEMBL585272 | 0.77 | STAT3 (0.55) | STAT3STAT1DHFRHDAC6HDAC3 | |
| SCHEMBL1856477 | 0.77 | STAT3 (0.50) | STAT3STAT1DHFRHDAC6HDAC3 | |
| SCHEMBL584793 | 0.77 | STAT3 (0.52) | STAT3STAT1DHFRHDAC6HDAC3 | |
| SCHEMBL1861760 | 0.77 | STAT3 (0.52) | STAT3STAT1CHEK2DYRK3MAP4K4 | |
| SCHEMBL12633119 | 0.76 | STAT3 (0.49) | STAT3STAT1DHFRHDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL584374 | 0.76 | STAT3 (0.51) | STAT3STAT1DHFRHDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL29883333 | 0.76 | STAT3 (0.51) | STAT3STAT1DHFRHDAC6HDAC3 | |
| SCHEMBL12057410 | 0.75 | STAT3 (0.47) | STAT3STAT1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558616-B2 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2011-08-24 | — | — | EP | disclosed |