Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12668290 | 0.96 | STAT3 (0.46) | STAT3STAT1PPARGPPARAHDAC6 | |
| SCHEMBL1856477 | 0.89 | STAT3 (0.50) | STAT3STAT1PPARGPPARAHDAC6 | |
| SCHEMBL585272 | 0.84 | STAT3 (0.55) | STAT3STAT1PPARGPPARAHDAC6 | |
| SCHEMBL1854874 | 0.84 | STAT3 (0.55) | STAT3STAT1PPARGPPARAHDAC6 | |
| SCHEMBL1861760 | 0.83 | STAT3 (0.52) | STAT3STAT1CHEK2DYRK3MAP4K4 | |
| SCHEMBL584793 | 0.83 | STAT3 (0.52) | STAT3STAT1PPARGPPARAHDAC6 | |
| Hydrochloric Acid SCHEMBL29883333 | 0.82 | STAT3 (0.51) | STAT3STAT1PPARGPPARAHDAC6 | |
| Hydrochloric Acid SCHEMBL584374 | 0.82 | STAT3 (0.51) | STAT3STAT1PPARGPPARAHDAC6 | |
| SCHEMBL4745594 | 0.81 | STAT3 (0.52) | STAT3STAT1PPARGPPARAHDAC6 | |
| SCHEMBL17722671 | 0.81 | STAT3 (0.49) | STAT3STAT1PPARGPPARAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |