Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 8/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192806 | 0.80 | PNMT (0.37) | PNMTADRA2AADRA2BADRA2CESR1 | |
| SCHEMBL6192228 | 0.80 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CESR1 | |
| SCHEMBL12450086 | 0.76 | PNMT (0.35) | PNMTADRA2AADRA2BADRA2CESR1 | |
| SCHEMBL2321696 | 0.74 | HTR7 (0.38) | PNMTADRA2AADRA2BADRA2CBRD4 | |
| SCHEMBL30294039 | 0.72 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CESR1 | |
| SCHEMBL31511298 | 0.72 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CESR1 | |
| SCHEMBL17018035 | 0.72 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CESR1 | |
| SCHEMBL16585592 | 0.72 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CESR1 | |
| SCHEMBL2779601 | 0.71 | MTNR1A (0.39) | PNMTADRA2AADRA2BADRA2CMTNR1A | |
| SCHEMBL2777471 | 0.71 | PNMT (0.38) | PNMTADRA2AADRA2BADRA2CMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097946-A1 | OXAZOLIDINONE COMPOUNDS CONTAINING RING-FUSED BICYCLIC RING, PREPARATION METHOD AND USE THEREOF | 山东轩竹医药科技有限公司 (CN) | 2011-08-18 | — | — | WO | disclosed |