SCHEMBL12451614

SCHEMBL12451614

CC1=NN(c2ccc(OC=O)cc2)C(=O)C1=Cc1c(C)nn(-c2ccc(C(=O)O)cc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KAT8 Q9H7Z6 10/20 0.53
▸ MEN1 O00255 5/20 0.52
▸ KMT2A Q03164 5/20 0.52
▸ EP300 Q09472 9/20 0.50
▸ ALDH1A1 P00352 2/20 0.48
▸ POLB P06746 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ USP2 O75604 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ SAE1 Q9UBE0 1/20 0.48
▸ UBA2 Q9UBT2 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ FNTA P49354 1/20 0.44
▸ FNTB P49356 1/20 0.44
▸ GPR55 Q9Y2T6 1/20 0.43
▸ GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12522408 0.91 KAT8 (0.63) KAT8MEN1KMT2AEP300ALDH1A1
SCHEMBL13092706 0.91 KAT8 (0.63) KAT8MEN1KMT2AEP300ALDH1A1
SCHEMBL12451617 0.89 KAT8 (0.46) KAT8MEN1KMT2AEP300ALDH1A1
SCHEMBL12451636 0.88 KAT8 (0.44) KAT8MEN1KMT2AEP300ALDH1A1
SCHEMBL420805 0.81 MAPT (0.60) KAT8MEN1KMT2AALDH1A1POLB
SCHEMBL445744 0.81 MAPT (0.60) KAT8MEN1KMT2AALDH1A1POLB
SCHEMBL8116198 0.81 MAPT (0.60) KAT8MEN1KMT2AALDH1A1POLB
SCHEMBL13092688 0.80 KAT8 (0.53) KAT8MEN1KMT2AEP300ALDH1A1
SCHEMBL12522411 0.80 KAT8 (0.53) KAT8MEN1KMT2AEP300ALDH1A1
SCHEMBL13377579 0.80 KAT8 (0.58) KAT8MEN1KMT2AEP300ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120237872-A1 BLACK AND WHITE SILVER HALIDE PHOTOSENSITIVE MATERIAL FUJIFILM CORPORATION (JP) 2012-09-20 — — US disclosed
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