SCHEMBL13377579

SCHEMBL13377579

CCc1nn(-c2ccc(C(=O)O)cc2)c(O)c1/C=C1\C(=O)N(c2ccc(C(=O)O)cc2)N=C1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KAT8 Q9H7Z6 10/20 0.58
▸ EP300 Q09472 8/20 0.54
▸ MEN1 O00255 5/20 0.53
▸ KMT2A Q03164 5/20 0.53
▸ FNTA P49354 1/20 0.48
▸ FNTB P49356 1/20 0.48
▸ GPR55 Q9Y2T6 1/20 0.46
▸ ALDH1A1 P00352 3/20 0.45
▸ MAPT P10636 3/20 0.45
▸ POLB P06746 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ SAE1 Q9UBE0 1/20 0.45
▸ UBA2 Q9UBT2 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ GAA P10253 1/20 0.45
▸ APEX1 P27695 1/20 0.44
▸ NTSR1 P30989 1/20 0.44
▸ GALK1 P51570 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14065942 0.90 EP300 (0.47) KAT8EP300MEN1KMT2AALDH1A1
SCHEMBL13092706 0.87 KAT8 (0.63) KAT8EP300MEN1KMT2AFNTA
SCHEMBL12522408 0.87 KAT8 (0.63) KAT8EP300MEN1KMT2AFNTA
SCHEMBL12451614 0.80 KAT8 (0.53) KAT8EP300MEN1KMT2AFNTA
SCHEMBL13092688 0.78 KAT8 (0.53) KAT8EP300MEN1KMT2AGPR55
SCHEMBL12270482 0.78 KAT8 (0.53) KAT8EP300MEN1KMT2AGPR55
SCHEMBL12522411 0.78 KAT8 (0.53) KAT8EP300MEN1KMT2AGPR55
SCHEMBL12589948 0.76 KMT2A (0.46) KAT8EP300MEN1KMT2AFNTA
SCHEMBL278669 0.76 KAT8 (0.51) KAT8EP300MEN1KMT2AGPR55
SCHEMBL14508083 0.76 KAT8 (0.51) KAT8EP300MEN1KMT2AGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1832928-B1 Planographic printing plate precursor, and stacks of the same FUJIFILM CORP (JP) 2010-04-28 — — EP disclosed
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