Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 7/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717725 | 0.86 | PTGS2 (0.48) | ESR1RAB9ANPC1HSD17B10PTGS2 | |
| SCHEMBL2369040 | 0.84 | MAPT (0.49) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2369039 | 0.84 | MAPT (0.49) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL28294576 | 0.83 | RAB9A (0.43) | ELANERECQLRAB9ANPC1HSD17B10 | |
| SCHEMBL28241536 | 0.83 | RAB9A (0.43) | ELANERECQLSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19357469 | 0.81 | ALDH1A1 (0.47) | ESR1SMN1; SMN2RAB9APTGS2ALDH1A1 | |
| SCHEMBL19357468 | 0.81 | ALDH1A1 (0.47) | ESR1SMN1; SMN2RAB9APTGS2ALDH1A1 | |
| SCHEMBL23931451 | 0.81 | RAB9A (0.41) | ELANEKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27573023 | 0.81 | RAB9A (0.41) | ELANEKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2882620 | 0.80 | ALDH1A1 (0.48) | ELANEKMT2ARAB9ANPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151452-A1 | OIL-IN-WATER-TYPE EMULSION COSMETIC | L V M H RECHERCHE (FR) | 2021-08-05 | — | — | WO | disclosed |
| WO-2017132655-A1 | PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-08-03 | — | — | WO | disclosed |
| EP-3185850-A1 | SKIN COLOR-IMPROVING AGENT AND COMPOSITION FOR IMPROVING SKIN COLOR | Showa Denko K.K. (JP) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016031634-A1 | SKIN COLOR-IMPROVING AGENT AND COMPOSITION FOR IMPROVING SKIN COLOR | SHOWA DENKO K. K. (JP) | 2016-03-03 | — | — | WO | disclosed |
| EP-2887921-A2 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE AND COMPOSITION AND COSMETIC CONTAINING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014030771-A2 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE AND COMPOSITION AND COSMETIC CONTAINING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2014-02-27 | — | — | WO | disclosed |
| US-20110082200-A1 | 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES | ALCON, INC. (CH) | 2011-04-07 | — | — | US | disclosed |
| US-7879905-B2 | treating persons suffering from age-related macular degeneration comprising administering 5,6,7-trihydroxyheptanoic acid analogs such as 5,6,7-trihydroxyheptanoic acid, methyl ester; vision defects | ALCON, INC. (CH) | 2011-02-01 | — | — | US | disclosed |
| EP-1809270-B1 | 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES | ALCON INC (CH) | 2010-03-24 | — | — | EP | disclosed |
| EP-1809270-A1 | 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES | ALCON INC. (CH) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006052950-A1 | 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES | ALCON, INC. (CH) | 2006-05-18 | — | — | WO | disclosed |
| US-20060099248-A1 | 5,6,7-Trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses | ALCON, INC. | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060099248-A1 | 5,6,7-Trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses | HPGDS, ADCYAP1R1, VEGFA | ELANE 826/4885ESR1 4319/4885RECQL 2031/4885 |
| US-20110082200-A1 | 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES | HPGDS, ADCYAP1R1, VEGFA | ELANE 826/4885ESR1 4319/4885RECQL 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.