Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | IGF2R | P11717 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250759 | 0.80 | RAB9A (0.61) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL20626855 | 0.78 | MAPK1 (0.59) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL19380827 | 0.77 | RAB9A (0.57) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL19359518 | 0.77 | RAB9A (0.57) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL4809812 | 0.77 | RAB9A (0.57) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL19359519 | 0.77 | RAB9A (0.57) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL11993126 | 0.77 | RAB9A (0.57) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL9539538 | 0.77 | RAB9A (0.53) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL9885403 | 0.76 | MAPK1 (0.53) | RAB9ANPC1PKMPOLBMAPT | |
| SCHEMBL5201027 | 0.76 | MAPK1 (0.66) | RAB9ANPC1PKMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148244-B2 | Medicines in controlling Vpr function | NIPPON SHINYAKU CO. LTD. (JP) | 2006-12-12 | — | — | US | claimed |
| US-6967211-B2 | Remedial agent for chronic articular rheumatism | NIPPON SHINYAKU CO. LTD. (JP) | 2005-11-22 | — | — | US | claimed |
| US-20040209927-A1 | Medicines | NIPPON SHINYAKU CO. LTD. (JP) | 2004-10-21 | — | — | US | claimed |
| US-20040116481-A1 | Remedial agent for chronic articular rheumatism | NIPPON SHINYAKU CO. LTD. (JP) | 2004-06-17 | — | — | US | claimed |
| EP-1382335-A1 | MEDICINES | Nippon Shinyaku Co., Ltd. (JP) | 2004-01-21 | — | — | EP | claimed |
| EP-1378237-A1 | REMEDIAL AGENT FOR CHRONIC ARTICULAR RHEUMATISM | Nippon Shinyaku Co., Ltd. (JP) | 2004-01-07 | — | — | EP | claimed |
| CN-102482704-B | New peptidase substrates | BIOMERIEUX (FR) | 2016-02-10 | — | — | CN | disclosed |
| EP-2459735-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | disclosed |
| EP-2459735-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012811-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |
| EP-1378237-A4 | REMEDIAL AGENT FOR CHRONIC ARTICULAR RHEUMATISM | NIPPON SHINYAKU CO LTD (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-1547596-A4 | MEDICINAL COMPOSITION AND METHOD FOR TREATING MALIGNANT TUMOR AND UTILIZATION THEREOF | WESTERN THERAPEUTICS INST INC (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-7148244-B2 | Medicines in controlling Vpr function | NIPPON SHINYAKU CO. LTD. (JP) | 2006-12-12 | — | — | US | disclosed |
| EP-0194472-B1 | Fluorescence polarization assay for macromolecular hydrolases. | ABBOTT LABORATORIES (US) | 1992-07-22 | — | — | EP | disclosed |
| US-5037615-A | Tethered pair fluorescence energy transfer indicators, chemical sensors, and method of making such sensors | CORDIS CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-4842783-A | Method of producing fiber optic chemical sensors incorporating photocrosslinked polymer gels | CORDIS CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0155330-B1 | AN IMPROVED FLUOROMETRIC ASSAY | ABBOTT LABORATORIES (US) | 1988-04-27 | — | — | EP | disclosed |
| EP-0194472-A2 | Fluorescence polarization assay for macromolecular hydrolases. | ABBOTT LABORATORIES (US) | 1986-09-17 | — | — | EP | disclosed |
| EP-0155330-A1 | An improved fluorometric assay | ABBOTT LABORATORIES (US) | 1985-09-25 | — | — | EP | disclosed |
| US-4495293-A | LIGAND, FLUORESCER AND REAGENT SYSTEM | ABBOTT LABORATORIES (US) | 1985-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209927-A1 | Medicines | SARS1, ADRA1B, ADRB1 | RAB9A 1223/4885NPC1 184/4885PKM 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.