SCHEMBL9250759

SCHEMBL9250759

OC(=Cc1ccccc1)c1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.61
NPC1 O15118 8/20 0.61
PKM P14618 3/20 0.61
POLB P06746 2/20 0.61
MAPT P10636 4/20 0.53
LMNA P02545 3/20 0.53
KDM4E B2RXH2 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.52
NAPRT Q6XQN6 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
GAA P10253 2/20 0.48
EGFR P00533 1/20 0.47
IGF1R P08069 1/20 0.47
IGF2R P11717 1/20 0.47
CCR6 P51684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245893 0.80 RAB9A (0.57) RAB9ANPC1PKMPOLBMAPT
SCHEMBL19359519 0.80 RAB9A (0.57) RAB9ANPC1PKMPOLBMAPT
SCHEMBL19380827 0.80 RAB9A (0.57) RAB9ANPC1PKMPOLBMAPT
SCHEMBL19359518 0.80 RAB9A (0.57) RAB9ANPC1PKMPOLBMAPT
SCHEMBL4809812 0.80 RAB9A (0.57) RAB9ANPC1PKMPOLBMAPT
SCHEMBL11993126 0.80 RAB9A (0.57) RAB9ANPC1PKMPOLBMAPT
SCHEMBL4102705 0.79 RAB9A (0.42) RAB9ANPC1PKMPOLBMAPT
SCHEMBL2773353 0.79 CYP19A1 (0.56) RAB9ANPC1PKMPOLBMAPT
SCHEMBL10578636 0.79 KMT2A (0.54) RAB9ANPC1PKMPOLBMAPT
SCHEMBL11374152 0.78 LMNA (0.56) RAB9ANPC1PKMPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088534-B1 ENHANCED DEPOSITION OF CHROMOGENS UTILIZING PYRIMIDINE ANALOGS VENTANA MED SYST INC (US) 2018-08-01 EP disclosed
EP-0347800-B1 Toner for electrostatic images MITSUBISHI GAS CHEMICAL CO (JP) 1995-02-22 EP disclosed
EP-0290860-B1 Thermosetting resin composition MITSUBISHI GAS CHEMICAL CO (JP) 1995-01-25 EP disclosed
US-4945138-A Styrylaza vinyl esters THE DOW CHEMICAL COMPANY (US) 1990-07-31 US disclosed
US-4925770-A COATING, PRIOR TO LIGHT EXPOSURE OF PHOTORESIST LAYER, A PHOTO-BLEACHABLE COMPOUND AND A WATER SOLUBLE POLYMER DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-05-15 US disclosed
US-4904760-A HEAT AND CHEMICAL RESISTANCE LOW DIELECTRIC MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1990-02-27 US disclosed
EP-0347800-A2 Toner for electrostatic images MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-12-27 EP disclosed
US-4883844-A FROM AROMATIC ALDEHYDE AND SUBSTITUTED PYRIDINE THE DOW CHEMICAL COMPANY (US) 1989-11-28 US disclosed
US-4851483-A FROM EPOXIDIZED HYDROXYSTYRYLAZA COMPOUNDS DERIVED FROM AROMATIC HYDROXYALDEHYDES AND METHYLATED PYRIDINES OR PYRAZINES THE DOW CHEMICAL COMPANY (US) 1989-07-25 US disclosed
EP-0290860-A2 Thermosetting resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1988-11-17 EP disclosed
EP-0246885-A2 A contrast-enhancing agent for photolithography Japan as represented by Director-General, Agency of Industrial Science and Technology (JP) 1987-11-25 EP disclosed
US-4540745-A Allyl styryl pyridines and pyrazines and polymers thereof THE DOW CHEMICAL COMPANY (US) 1985-09-10 US disclosed
US-4539377-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1985-09-03 US disclosed