Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 8/20 | 0.48 |
| ▸ | PPIG | Q13427 | 5/20 | 0.45 |
| ▸ | PPIB | P23284 | 3/20 | 0.45 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14818001 | 0.88 | SMN1; SMN2 (0.52) | AADATHSD11B1ADAM17PRMT5WDR77 | |
| SCHEMBL14644451 | 0.83 | PPID (0.73) | PPIDPPIGPPIB | |
| SCHEMBL19409993 | 0.83 | HSD11B1 (0.48) | HSD11B1ADAM17PRMT5WDR77NPC1 | |
| SCHEMBL19961321 | 0.83 | ALDH1A1 (0.48) | AADATSIGMAR1 | |
| SCHEMBL38659451 | 0.79 | HSD11B1 (0.51) | HSD11B1ADAM17PRMT5WDR77NPC1 | |
| SCHEMBL8296762 | 0.79 | HSD11B1 (0.51) | HSD11B1ADAM17PRMT5WDR77NPC1 | |
| SCHEMBL1329027 | 0.77 | HSD11B1 (0.55) | HSD11B1ADAM17PRMT5WDR77NPC1 | |
| SCHEMBL31430923 | 0.75 | PRMT5 (0.55) | HSD11B1ADAM17PRMT5WDR77NPC1 | |
| SCHEMBL29504572 | 0.75 | PRMT5 (0.55) | HSD11B1ADAM17PRMT5WDR77NPC1 | |
| SCHEMBL2043216 | 0.75 | PPIB (0.70) | PPIDPPIGPPIBHSD11B1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343303-A1 | PI3-kinase inhibitors | Boehringer Ingelheim International GmbH (DE) | 2011-07-13 | — | — | EP | disclosed |