Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459662 | 0.88 | PPID (0.48) | AADATPRMT5WDR77PRCPNPC1 | |
| SCHEMBL19961321 | 0.83 | ALDH1A1 (0.48) | KDM4EAADATPOLBALDH1A1MAPT | |
| SCHEMBL13212080 | 0.82 | PRMT5 (0.53) | KDM4EPRMT5WDR77NPC1RAB9A | |
| SCHEMBL19409993 | 0.80 | HSD11B1 (0.48) | PRMT5WDR77NPC1RAB9AHSD11B1 | |
| SCHEMBL9289727 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EAADATPRCPDRD4 | |
| SCHEMBL1329027 | 0.77 | HSD11B1 (0.55) | PRMT5WDR77NPC1RAB9AHSD11B1 | |
| SCHEMBL38659451 | 0.76 | HSD11B1 (0.51) | PRMT5WDR77NPC1RAB9AHSD11B1 | |
| SCHEMBL8296762 | 0.76 | HSD11B1 (0.51) | PRMT5WDR77NPC1RAB9AHSD11B1 | |
| SCHEMBL2306967 | 0.74 | HHAT (0.55) | PRCP | |
| SCHEMBL12567634 | 0.73 | PRCP (0.51) | SMN1; SMN2KDM4EAADATPRCPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802636-B1 | PI3 KINASES INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2013-03-27 | — | — | EP | disclosed |