Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148285 | 0.79 | POLB (0.42) | PKMPIM1MEN1KMT2AALDH1A1 | |
| SCHEMBL10752092 | 0.67 | LMNA (0.44) | CYP3A4CYP2C9KDM4E | |
| SCHEMBL16982082 | 0.67 | HTR3A (0.41) | HTR3APIM1HRH4CHEK1MEN1 | |
| SCHEMBL14770091 | 0.62 | — | — | |
| SCHEMBL16982109 | 0.62 | POLB (0.42) | — | |
| Bicarbonate SCHEMBL16668956 | 0.62 | CYP1A2 (0.58) | ALDH1A1CYP1A2KDM4EHTT | |
| SCHEMBL64557 | 0.61 | NPC1 (0.47) | HTR3AHRH4NPC1RAB9AALDH1A1 | |
| SCHEMBL4174000 | 0.61 | PIM1 (0.39) | HTR3APIM1HRH4MEN1KMT2A | |
| SCHEMBL2800959 | 0.60 | PRKAB2 (0.39) | CHEK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL23960950 | 0.60 | CHEK1 (0.48) | HTR3ACHEK1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364610-A1 | COMPOUND SUITABLE FOR THE TREATMENT OF SYNUCLEOPATHIES | NEUROPORE THERAPIES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8846682-B2 | Compound suitable for the treatment of synucleopathies | NEUROPORE THERAPIES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130035342-A1 | Compound Suitable for the Treatment of Synucleopathies | NEUROPORE THERAPIES, INC. (US) | 2013-02-07 | — | — | US | disclosed |
| WO-2011084642-A1 | COMPOUND SUITABLE FOR THE TREATMENT OF SYNUCLEOPATHIES | NEUROPORE THERAPIES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035342-A1 | Compound Suitable for the Treatment of Synucleopathies | SNCA, HTT, SMN1; SMN2 | HTR3A 1462/4885PKM 2644/4885PIM1 4062/4885 |
| US-20140364610-A1 | COMPOUND SUITABLE FOR THE TREATMENT OF SYNUCLEOPATHIES | SNCA, HTT, MAPT | HTR3A 1803/4885PKM 552/4885PIM1 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.