Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541706 | 1.00 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3260470 | 1.00 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL26978842 | 1.00 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1049466 | 1.00 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22836423 | 1.00 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17981462 | 1.00 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2467407 | 1.00 | MAPT (0.57) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5153957 | 0.98 | TSHR (0.58) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1444871 | 0.91 | — | — | |
| SCHEMBL18102172 | 0.89 | ALDH1A1 (0.54) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005029003-A2 | IDENTIFICATION OF AIR COMPONENTS WITH SILICON MASS SPECTROMETRY | WATERS INVESTMENTS LIMITED (US) | 2005-03-31 | — | — | WO | claimed |
| US-20240084343-A1 | METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION | KIVERDI INC (US) | 2024-03-14 | — | — | US | disclosed |
| WO-2024027706-A1 | BCL-XL DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-02-08 | — | — | WO | disclosed |
| US-10144638-B2 | Methods of dispersing carbon nanotubes | BATTELLE MEMORIAL INSTITUTE (US) | 2018-12-04 | — | — | US | disclosed |
| EP-2085220-B1 | Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same | FUJIFILM CORP (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-8273520-B2 | Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same | FUJIFILM CORPORATION (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8273520-B2 | Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same | FUJIFILM CORPORATION (JP) | 2012-09-25 | — | — | US | disclosed |
| EP-2459510-A1 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS | Phenomenome Discoveries Inc. (CA) | 2012-06-06 | — | — | EP | disclosed |
| US-20120136057-A1 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS | PHENOMENOME DISCOVERIES INC. (CA) | 2012-05-31 | — | — | US | disclosed |
| US-20120136057-A1 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS | PHENOMENOME DISCOVERIES INC. (CA) | 2012-05-31 | — | — | US | disclosed |
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |
| US-6358613-B1 | SILICON SUBSTRATE WITH LAYERS OF VINYL OR ALKYL GROUPS BONDED TO SILICON SURFACE | PURDUE RESEARCH FOUNDATION | 2002-03-19 | — | — | US | disclosed |
| EP-1166329-A1 | IMPROVED DESORPTION/IONIZATION OF ANALYTES FROM POROUS LIGHT-ABSORBING SEMICONDUCTOR | The Scripps Research Institute (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6288390-B1 | Desorption/ionization of analytes from porous light-absorbing semiconductor | SCRIPPS RESEARCH INSTITUTE | 2001-09-11 | — | — | US | disclosed |
| EP-1056548-A1 | FUNCTIONALIZED POROUS SILICON SURFACES | PURDUE RESEARCH FOUNDATION (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-2000054309-A1 | IMPROVED DESORPTION/IONIZATION OF ANALYTES FROM POROUS LIGHT-ABSORBING SEMICONDUCTOR | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-09-14 | — | — | WO | disclosed |
| WO-1999037409-A1 | FUNCTIONALIZED POROUS SILICON SURFACES | PURDUE RESEARCH FOUNDATION (US) | 1999-07-29 | — | — | WO | disclosed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |
| US-4450149-A | REASCTING AN ORGANIC BORANE WITH A RADIOACTIVE HALOMONOCHLORIDE AND A MILD OXIDIZER; RADIOLOGY | RESEARCH CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136057-A1 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS | HCAR2, ALOX5, ALOX12 | MAPT 3727/4885CYP1A2 506/4885CYP2D6 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.