SCHEMBL2467407

SCHEMBL2467407

C#CCCCCCCCC(=O)OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TSHR P16473 3/20 0.56
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
KMT2A Q03164 2/20 0.46
RECQL P46063 1/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
EPHX2 P34913 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15541706 1.00 MAPT (0.57) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL3260470 1.00 MAPT (0.57) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1246192 1.00 MAPT (0.57) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL26978842 1.00 MAPT (0.57) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1049466 1.00 MAPT (0.57) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL22836423 1.00 MAPT (0.57) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL17981462 1.00 MAPT (0.57) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL5153957 0.98 TSHR (0.58) MAPTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1444871 0.91
SCHEMBL18102172 0.89 ALDH1A1 (0.54) MAPTCYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479812-B2 Fatty acid derivatives and their use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-11-25 US disclosed
US-20250325512-A1 Neurodegenerative Disorders And Muscle Diseases Implicating Pufas BIOJIVA LLC (US) 2025-10-23 US disclosed
US-12156860-B2 Disorders implicating PUFA oxidation BIOJIVA LLC (US) 2024-12-03 US disclosed
WO-2024027706-A1 BCL-XL DEGRADING COMPOUNDS BEIJING NEOX BIOTECH LIMITED (CN) 2024-02-08 WO disclosed
US-20230404960-A1 DISORDERS IMPLICATING PUFA OXIDATION BIOJIVA LLC (US) 2023-12-21 US disclosed
US-11555021-B2 Fatty acid derivatives and their use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-01-17 US disclosed
US-20220378734-A1 NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS RTMFP ENTERPRISES INC. 2022-12-01 US disclosed
US-11510888-B2 Alleviating oxidative stress disorders with PUFA derivatives RETROTOPE, INC. (US) 2022-11-29 US disclosed
US-RE49238-E1 Alleviating oxidative stress disorders with PUFA derivatives RETROTOPE, INC. (US) 2022-10-11 US disclosed
US-20220304968-A1 OXIDATIVE RETINAL DISEASES BIOJIVA LLC 2022-09-29 US disclosed
EP-3649115-A1 FATTY ACID DERIVATIVES AND THEIR USE The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) 2020-05-13 EP disclosed
WO-2019010414-A1 FATTY ACID DERIVATIVES AND THEIR USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2019-01-10 WO disclosed
US-9248145-B2 Two alkylresorcinol synthase genes from sorghum; cloning, expression, transformation and characterization THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2016-02-02 US disclosed
CN-103664604-B Bromo-9,11,19-tri-alkynes-17, the 21-diene behenic acid Lipase absobed methods of bromination yne compounds E, E-22- SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2015-11-04 CN disclosed
CN-103664604-A Synthesis method of brominated eneyne compound E,E-22-bromo-9,11,19-trialkynyl-17,21-diene behenate SHANGHAI INST MATERIA MEDICA 2014-03-26 CN disclosed
US-20110225676-A1 Two Novel Alkylresorcinol Synthase Genes from Sorghum; Cloning, Expression, Transformation and Characterization THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2011-09-15 US disclosed
US-20090317660-A1 Methods of Dispersing Carbon Nanotubes BATTELLE MEMORIAL INSTITUTE 2009-12-24 US disclosed
US-20090317660-A1 Methods of Dispersing Carbon Nanotubes BATTELLE MEMORIAL INSTITUTE 2009-12-24 US disclosed
WO-2008054472-A9 METHODS OF DISPERSING CARBON NANOTUBES BATTELLE MEMORIAL INSTITUTE (US) 2008-08-07 WO disclosed
WO-2008054472-A2 METHODS OF DISPERSING CARBON NANOTUBES BATTELLE MEMORIAL INSTITUTE (US) 2008-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220378734-A1 NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS CPT1B, PSEN2, NLN MAPT 115/4885CYP1A2 4231/4885CYP2D6 4534/4885
US-12156860-B2 Disorders implicating PUFA oxidation GPX4, CPT1A, FABP1 MAPT 4766/4885CYP1A2 187/4885CYP2D6 391/4885
US-20220304968-A1 OXIDATIVE RETINAL DISEASES ALDH1A2, TXNRD2, STARD3 MAPT 875/4885CYP1A2 2855/4885CYP2D6 3218/4885
US-20230404960-A1 DISORDERS IMPLICATING PUFA OXIDATION GPX4, CPT1A, FABP1 MAPT 4766/4885CYP1A2 187/4885CYP2D6 391/4885
US-20250325512-A1 Neurodegenerative Disorders And Muscle Diseases Implicating Pufas CPT1B, PSEN2, NLN MAPT 115/4885CYP1A2 4231/4885CYP2D6 4534/4885
US-12479812-B2 Fatty acid derivatives and their use FFAR3, FFAR1, FFAR2 MAPT 193/4885CYP1A2 1129/4885CYP2D6 1144/4885
US-11555021-B2 Fatty acid derivatives and their use FFAR3, FFAR1, FFAR2 MAPT 193/4885CYP1A2 1129/4885CYP2D6 1144/4885
US-11510888-B2 Alleviating oxidative stress disorders with PUFA derivatives GPX4, ALOX12, ALOX15 MAPT 945/4885CYP1A2 2113/4885CYP2D6 3168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.