Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031587 | 0.89 | POLB (0.68) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL10031598 | 0.82 | MEN1 (0.70) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL21637832 | 0.81 | USP2 (0.71) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL12010926 | 0.80 | HSD11B1 (0.68) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL5453637 | 0.77 | PDE4A (0.71) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL290584 | 0.77 | ALDH1A1 (0.71) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL10031617 | 0.77 | USP2 (0.69) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL13651634 | 0.77 | USP2 (0.69) | POLBALDH1A1LMNAKDM4EUSP2 | |
| Sulfisomidine SCHEMBL34791 | 0.76 | PDE4A (1.00) | POLBALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL1828300 | 0.76 | PDE4A (0.74) | POLBALDH1A1LMNAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1826001-B1 | A heat-sensitive positive-working lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2011-07-06 | — | — | EP | disclosed |