Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464636 | 0.92 | MAPT (0.37) | PSMB5FFAR1BCHEALDH1A1HPGD | |
| SCHEMBL2158270 | 0.83 | PTPN22 (0.38) | PSMB5MEN1KMT2A | |
| SCHEMBL2158355 | 0.76 | CCR2 (0.36) | PSMB5FFAR1BCHEALDH1A1MEN1 | |
| SCHEMBL2158082 | 0.76 | NPC1 (0.34) | ALDH1A1HPGD | |
| SCHEMBL2158053 | 0.72 | CYP3A4 (0.43) | — | |
| SCHEMBL2157707 | 0.71 | PTGES (0.45) | KMT2A | |
| SCHEMBL3807323 | 0.70 | NPC1 (0.49) | KMT2A | |
| SCHEMBL13270878 | 0.69 | PTPN1 (0.46) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2158108 | 0.68 | STAT3 (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6426884 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |