Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158539 | 0.88 | ALDH1A1 (0.41) | LTB4R2SLC6A2SLC6A4KDM4ESMN1; SMN2 | |
| SCHEMBL2157764 | 0.87 | MEN1 (0.44) | LTB4R2ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL2158746 | 0.85 | LTB4R2 (0.52) | LTB4R2MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL12464657 | 0.85 | LTB4R2 (0.50) | LTB4R2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12464658 | 0.82 | LTB4R2 (0.39) | LTB4R2SLC6A2SLC6A4SLC6A3PTGER1 | |
| SCHEMBL2157724 | 0.79 | MAPT (0.38) | LTB4R2SLC6A2SLC6A4MAPTKDM4E | |
| SCHEMBL2157858 | 0.78 | TACR1 (0.40) | LTB4R2MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL3814627 | 0.77 | MAPT (0.38) | LTB4R2SLC6A2SLC6A4MAPTKDM4E | |
| SCHEMBL6625466 | 0.77 | LTB4R2 (0.47) | LTB4R2MAPTKDM4EHTTALDH1A1 | |
| SCHEMBL2157674 | 0.75 | PTGDR2 (0.42) | LTB4R2SLC6A2SLC6A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |