Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407275 | 1.00 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CHRM3HTTTHRB | |
| SCHEMBL14376725 | 1.00 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CHRM3HTTTHRB | |
| SCHEMBL15806857 | 0.94 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1CHRM3HTTTHRB | |
| SCHEMBL29306619 | 0.85 | TRPV6 (0.39) | DRD2TRPV6CASP3CASP7 | |
| SCHEMBL24917605 | 0.84 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CHRM3HTTTHRB | |
| SCHEMBL22281053 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A1L3MBTL1CHRM3HTTDRD2 | |
| SCHEMBL8391212 | 0.82 | HDAC8 (0.44) | ALDH1A1L3MBTL1CHRM3HTTDRD2 | |
| SCHEMBL8391210 | 0.82 | HDAC8 (0.44) | ALDH1A1L3MBTL1CHRM3HTTDRD2 | |
| SCHEMBL4749550 | 0.82 | HDAC8 (0.44) | ALDH1A1L3MBTL1CHRM3HTTDRD2 | |
| SCHEMBL28284569 | 0.81 | CASP3 (0.34) | ALDH1A1CYP1A2SMN1; SMN2TRPV6CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183938-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183938-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | CHEK1, CHEK2, BUB1B | ALDH1A1 576/4885L3MBTL1 2201/4885CHRM3 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.