Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245358 | 0.95 | NR1H4 (0.42) | NR1H4PPARDALDH1A1MAPTFABP1 | |
| SCHEMBL1245176 | 0.93 | NR1H4 (0.40) | NR1H4PPARDALDH1A1MAPTFABP1 | |
| SCHEMBL1245136 | 0.93 | NR1H4 (0.38) | NR1H4PPARDALDH1A1MAPTPTGDR2 | |
| SCHEMBL1245335 | 0.92 | NR1H4 (0.50) | NR1H4PPARDMAPTFABP1FABP4 | |
| SCHEMBL1246476 | 0.90 | NR1H4 (0.42) | NR1H4PPARDALDH1A1MAPTFABP1 | |
| SCHEMBL1246467 | 0.90 | NR1H4 (0.43) | NR1H4PPARDFABP1FABP4GPBAR1 | |
| SCHEMBL1247804 | 0.88 | NPSR1 (0.37) | NR1H4PPARDALDH1A1MAPTPTGDR2 | |
| SCHEMBL1246346 | 0.87 | SCN9A (0.38) | NR1H4PPARDALDH1A1MAPTGPBAR1 | |
| SCHEMBL1247748 | 0.87 | SCN9A (0.39) | NR1H4PPARDALDH1A1MAPTFABP1 | |
| SCHEMBL1245294 | 0.87 | GPBAR1 (0.37) | ALDH1A1MAPTPTGDR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462128-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-06-13 | — | — | EP | claimed |
| WO-2011017350-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | WO | claimed |