SCHEMBL124652

SCHEMBL124652

[CH2]C(O)COc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.63
CYP2D6 P10635 3/20 0.50
SCN4A P35499 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ADRB2 P07550 1/20 0.50
ADRB1 P08588 1/20 0.50
ADRB3 P13945 1/20 0.50
KDM4E B2RXH2 1/20 0.49
MAPT P10636 2/20 0.47
RECQL P46063 2/20 0.47
TSHR P16473 1/20 0.47
HIF1A Q16665 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAOA P21397 1/20 0.47
PTGS1 P23219 1/20 0.47
ALDH1A1 P00352 1/20 0.46
KCNA3 P22001 1/20 0.46
MTNR1A P48039 3/20 0.46
MTNR1B P49286 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11649114 0.83 MAPT (0.56) LMNACYP2D6L3MBTL1ADRB2ADRB1
SCHEMBL9564637 0.81 LMNA (0.68) LMNACYP2D6SCN4AL3MBTL1ADRB2
SCHEMBL267463 0.81 LMNA (0.68) LMNACYP2D6SCN4AL3MBTL1ADRB2
SCHEMBL345402 0.81 LMNA (0.68) LMNACYP2D6SCN4AL3MBTL1ADRB2
SCHEMBL544769 0.79 LMNA (0.66) LMNACYP2D6SCN4AL3MBTL1ADRB2
SCHEMBL1759547 0.78 TSHR (0.45) MAPTTSHRMAOA
SCHEMBL749890 0.78 KCNA3 (0.54) LMNARECQLALDH1A1KCNA3
SCHEMBL8747584 0.78 CYP1A2 (0.53) LMNASCN4ATSHRALDH1A1
SCHEMBL11108265 0.78 LMNA (0.59) LMNACYP2D6SCN4AL3MBTL1ADRB2
SCHEMBL8479002 0.78 TDP1 (0.48) LMNAL3MBTL1ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7882 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240046-A1 ANTIREFLECTION FILM, LAMINATE HAVING ANTIREFLECTION FILM, AND METHOD FOR MANUFACTURING ANTIREFLECTION FILM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-07-18 US claimed
CN-112912411-B Photocurable composition, cured film, and laminate 捷恩智株式会社 2024-07-09 CN claimed
CN-118308049-A Water-based polyurethane binder, preparation method thereof and application thereof in new energy battery 安徽大学绿色产业创新研究院 2024-07-09 CN claimed
US-11998621-B2 Transparent, fracture-tough polymerization resins for the production of dental shaped bodies IVOCLAR VIVADENT AG (LI) 2024-06-04 US claimed
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP claimed
EP-4349589-A1 ANTIREFLECTION FILM, LAMINATE HAVING ANTIREFLECTION FILM, AND METHOD FOR MANUFACTURING ANTIREFLECTION FILM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-10 EP claimed
US-11952450-B2 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2024-04-09 US claimed
US-20240026127-A1 COMPOSITE PARTICLE AND USE THEREOF IN OPTICAL FILTRATION COLOURSMITH LABS INC. (CA) 2024-01-25 US claimed
CN-117203049-A Antireflection film, laminate having antireflection film, and method for producing antireflection film 三菱瓦斯化学株式会社 2023-12-08 CN claimed
WO-2023230984-A1 AQUEOUS POLYMER EMULSION AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2023-12-07 WO claimed
US-4582833-A HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1986-04-15 US claimed
EP-0171702-A1 Benzoxazinone derivatives, preparation and use BEECHAM GROUP PLC (GB) 1986-02-19 EP claimed
US-4496480-A Isothiazolazo dyes having coupling components which are free from unsaturated aliphatic radicals BASF AKTIENGESELLSCHAFT (DE) 1985-01-29 US claimed
EP-0020293-B1 STABILISING COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1984-05-23 EP claimed
US-4432899-A Preparing concentrated azo dye solutions using nitrite salt as both coupling component and diazotizing agent BAYER AKTIENGESELLSCHAFT (DE) 1984-02-21 US claimed
US-4349549-A Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s SYNTEX (U.S.A.) INC. (US) 1982-09-14 US claimed
US-4309546-A Piperidino pyrrolidinones CIBA-GEIGY CORPORATION (US) 1982-01-05 US claimed
US-4233214-A FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-11-11 US claimed
US-4036826-A Cationic azo dyestuffs with a hydroxyalkylated ammonium group BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US claimed
US-3998953-A 1,3,7-Trisubstitued xanthine peripheral vasodilators BOEHRINGER INGELHEIM GMBH (DT) 1976-12-21 US claimed