Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246900 | 0.81 | ALDH1A1 (0.56) | CYP2C9KDM4ENPSR1MAPK1TAAR1 | |
| SCHEMBL5278210 | 0.78 | TAAR1 (0.53) | KDM4ENPSR1TAAR1LMNAALDH1A1 | |
| SCHEMBL1226543 | 0.73 | NQO2 (0.59) | KDM4ENPSR1MAPK1LMNARXFP1 | |
| SCHEMBL1244922 | 0.71 | ALOX5 (0.61) | CYP3A4KDM4ENPSR1TDP1TAAR1 | |
| SCHEMBL1246644 | 0.71 | MAPT (0.54) | KDM4EMAPK1TAAR1LMNARXFP1 | |
| D-Alanine SCHEMBL1246484 | 0.70 | ALDH1A1 (0.55) | CYP2C9KDM4ENPSR1MAPK1LMNA | |
| Alanine SCHEMBL1246935 | 0.70 | ALDH1A1 (0.55) | CYP2C9KDM4ENPSR1MAPK1LMNA | |
| SCHEMBL1245863 | 0.70 | CHAT (0.57) | KDM4ENPSR1MAPK1TAAR1LMNA | |
| SCHEMBL1244759 | 0.69 | ATG4B (0.56) | CYP2C9KDM4EMAPK1LMNAALDH1A1 | |
| SCHEMBL10964842 | 0.69 | METAP1 (0.54) | CYP3A4CYP2C9KDM4ENPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | claimed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | claimed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | claimed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | claimed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | claimed |
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | disclosed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | disclosed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | disclosed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122135-A1 | Novel Peptidase Substrates | CPN1, CTRL, ANPEP | CYP3A4 758/4885CYP2C9 1543/4885KDM4E 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.