Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.59 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466797 | 0.79 | MEN1 (0.77) | F2TPSAB1PRSS1PRSS2PRSS3 | |
| SCHEMBL6429540 | 0.76 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL15077021 | 0.74 | F2 (0.74) | F2FKBP1A | |
| SCHEMBL23752396 | 0.74 | F2 (0.74) | F2FKBP1A | |
| SCHEMBL21138521 | 0.74 | HSD11B1 (0.62) | HSD11B1 | |
| SCHEMBL4964339 | 0.73 | HSD11B1 (0.61) | HSD11B1 | |
| SCHEMBL4629395 | 0.73 | HSD11B1 (0.61) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL29238125 | 0.72 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL27651068 | 0.71 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL15077024 | 0.71 | F2 (0.74) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668157-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | Proximagen Limited (GB) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012101453-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | PROXIMAGEN LTD. (GB) | 2012-08-02 | — | — | WO | disclosed |