Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840854 | 0.79 | NR1H4 (0.70) | NR1H4EPHX2RXRARXRBRXRG | |
| SCHEMBL27940962 | 0.79 | RXRA (0.58) | NR1H4EPHX2RXRARXRBRXRG | |
| SCHEMBL3385203 | 0.79 | PTPN1 (0.66) | PTPN1PTPN2PTPN6PTPN11 | |
| SCHEMBL1061936 | 0.77 | RXRA (0.56) | NR1H4EPHX2RXRARXRBRXRG | |
| Methane SCHEMBL17237476 | 0.77 | NR1H4 (0.68) | NR1H4EPHX2RXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL2528372 | 0.77 | NR1H4 (0.68) | NR1H4EPHX2RXRARXRBRXRG | |
| SCHEMBL11520885 | 0.76 | RXRA (0.54) | NR1H4EPHX2RXRARXRBRXRG | |
| SCHEMBL9785033 | 0.76 | RXRA (0.54) | NR1H4EPHX2RXRARXRBRXRG | |
| SCHEMBL21133929 | 0.76 | RXRA (0.54) | NR1H4EPHX2RXRARXRBRXRG | |
| SCHEMBL7182175 | 0.76 | RXRA (0.54) | NR1H4EPHX2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10159750-B2 | Immunogenic compositions and reagents for preparing | PURDUE RESEARCH FOUNDATION (US) | 2018-12-25 | — | — | US | disclosed |
| US-20180289820-A1 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING | PURDUE RESEARCH FOUNDATION (US) | 2018-10-11 | — | — | US | disclosed |
| US-10010616-B2 | Immunogenic compositions and reagents for preparing | PURDUE RESEARCH FOUNDATION (US) | 2018-07-03 | — | — | US | disclosed |
| US-20150023987-A1 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING | PURDUE RESEARCH FOUNDATION (US) | 2015-01-22 | — | — | US | disclosed |
| WO-2012103444-A2 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING | PURDUE RESEARCH FOUNDATION (US) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150023987-A1 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING | FCGRT, HLA-DRB1, CD47 | NR1H4 3497/4885EPHX2 378/4885RXRA 3687/4885 |
| US-20180289820-A1 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING | FCGRT, HLA-DRB1, CD47 | NR1H4 3497/4885EPHX2 378/4885RXRA 3687/4885 |
| US-10159750-B2 | Immunogenic compositions and reagents for preparing | FCGRT, HLA-DRB1, CD47 | NR1H4 3497/4885EPHX2 378/4885RXRA 3687/4885 |
| US-10010616-B2 | Immunogenic compositions and reagents for preparing | FCGRT, HLA-DRB1, CD47 | NR1H4 3497/4885EPHX2 378/4885RXRA 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.