SCHEMBL7182175

SCHEMBL7182175

CC(C)(C(=O)O)c1ccc(CC(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.54
RXRB P28702 2/20 0.54
RXRG P48443 2/20 0.54
NR1H4 Q96RI1 7/20 0.53
EPHX2 P34913 1/20 0.53
CA2 P00918 1/20 0.52
CAMK2A Q9UQM7 1/20 0.52
AKR1B1 P15121 1/20 0.50
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ABCC4 O15439 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 1/20 0.48
PTGS1 P23219 1/20 0.48
HTT P42858 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
KLKB1 P03952 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11217385 0.85 HRH3 (0.41) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL27940962 0.83 RXRA (0.58) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL840854 0.83 NR1H4 (0.70) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL3497043 0.82 MAPT (0.52) ALDH1A1TSHRCYP2C19
SCHEMBL23582939 0.82 NR1H4 (0.51) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL55105 0.82 PPARA (0.55) EPHX2TSHR
SCHEMBL127737 0.82 ALDH1A1 (0.52) RXRARXRBALDH1A1HPGD
Methane SCHEMBL17237476 0.82 NR1H4 (0.68) RXRARXRBRXRGNR1H4EPHX2
Hydrochloric Acid SCHEMBL2528372 0.82 NR1H4 (0.68) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL1061936 0.82 RXRA (0.56) RXRARXRBRXRGNR1H4EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108863850-B Biaryl compound and preparation method and application thereof 复旦大学 2021-05-18 CN disclosed
US-20170255100-A1 DRY FILM STRUCTURE FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-07 US disclosed
US-6600080-B1 Method of alcohols such as cyclohexanedimethanol, a benzyl ester is obtained, for example, by the reaction between a benzyl compound and carboxylic acid in the presence of oxygen and a catalyst including palladium, gold ultra fine particles NIPPON SHOKUBAI CO., LTD. (JP) 2003-07-29 US disclosed
EP-1090902-A2 Method for producing alcohols such as cyclohexanedimethanol Nippon Shokubai Co., Ltd. (JP) 2001-04-11 EP disclosed
US-4016194-A CATALYTIC CARBONYLATION TEXACO INC. (US) 1977-04-05 US disclosed
US-3966656-A FIBER AND FILM FORMING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-29 US disclosed