Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149738 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL12654001 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL31376280 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL18648382 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL15894812 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL106356 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL12467707 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL12315986 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL21003882 | 0.96 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL13185737 | 0.94 | SOAT2 (0.82) | SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228376-B1 | PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY | KITASATO INST (JP) | 2015-06-03 | — | — | EP | disclosed |
| US-8519128-B2 | Pyripyropene derivatives having an ACAT2-inhibiting activity | THE KITASATO INSTITUTE (JP) | 2013-08-27 | — | — | US | disclosed |
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | THE KITASATO INSTITUTE (JP) | 2011-07-28 | — | — | US | disclosed |
| EP-2228376-A1 | PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY | The Kitasato Institute (JP) | 2010-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | ACAT2, ACAT1, AGPAT2 | SOAT2 36/4885SOAT1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.