Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21003882 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL19149738 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL15894812 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL12315986 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL12467707 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL12654001 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL31376280 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL18648382 | 1.00 | SOAT2 (1.00) | SOAT2SOAT1 | |
| SCHEMBL12467442 | 0.96 | SOAT2 (0.92) | SOAT2SOAT1 | |
| SCHEMBL12467763 | 0.95 | SOAT2 (1.00) | SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605359-B2 | Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor and pharmaceutical use therefor | THE KITASATO INSTITUTE (JP) | 2026-04-21 | — | — | US | claimed |
| CN-119265049-B | Bacterial strain for producing pyripyropene A and application thereof | 鲁东大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119265049-A | Bacterial strain for producing pyripyropene A and application thereof | 鲁东大学 | 2025-01-07 | — | — | CN | claimed |
| CN-116904328-B | Engineering bacterium for high-expression of pyripyropene A and fermentation medium | 山东大学 | 2024-08-02 | — | — | CN | claimed |
| US-11911469-B2 | Combination of ACAT1 inhibitor and checkpoint antibody for treating cancer | Center for Excellence in Molecular Cell Science, Chinese Academy of Scienes (CN) | 2024-02-27 | — | — | US | claimed |
| CN-116904328-A | Engineering bacterium for high-expression of pyripyropene A and fermentation medium | 山东大学 | 2023-10-20 | — | — | CN | claimed |
| US-11571400-B2 | ACAT1 inhibitors for treating cancer | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2023-02-07 | — | — | US | claimed |
| CN-106032383-B | A kind of tricyclic analog, preparation method and use | 中国科学院上海药物研究所 | 2019-08-13 | — | — | CN | claimed |
| EP-2945949-B1 | METHOD FOR PREPARING A PYRIPYROPENE COMPOUND | BASF SE (DE) | 2019-05-15 | — | — | EP | claimed |
| US-10278962-B2 | Tricyclic analogues, preparation method and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2019-05-07 | — | — | US | claimed |
| WO-2014205109-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND MANAGEMENT OF STEATOSIS IN HUMAN LIVER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2014-12-24 | — | — | WO | claimed |
| CN-104017839-A | Method for manufacturing a pyripyropene | MEIJI SEIKA PHARMA CO LTD | 2014-09-03 | — | — | CN | claimed |
| US-20140142289-A1 | PYRIPYROPENE A BIOSYNTHETIC GENE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-05-22 | — | — | US | claimed |
| CN-103536922-A | Application of acyl-coenzyme A: cholesterol acyltransferase-2 (ACAT2) inhibitor in liver cancer growth inhibition | SHANGHAI INST BIOL SCIENCES | 2014-01-29 | — | — | CN | claimed |
| EP-2319923-B1 | PYRIPYROPENE A BIOSYNTHETIC GENES | MEIJI SEIKA PHARMA CO LTD (JP) | 2013-12-25 | — | — | EP | claimed |
| US-8557550-B2 | Pyripyropene a biosynthetic gene | Meija Seika Pharma Co., Ltd. (JP) | 2013-10-15 | — | — | US | claimed |
| US-20130023017-A1 | METHOD FOR PRODUCING PYRIPYROPENE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2013-01-24 | — | — | US | claimed |
| EP-2530164-A1 | METHOD FOR MANUFACTURING A PYRIPYROPENE | Meiji Seika Pharma Co., Ltd. (JP) | 2012-12-05 | — | — | EP | claimed |
| US-20120015410-A1 | PYRIPYROPENE A BIOSYNTHETIC GENE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2012-01-19 | — | — | US | claimed |
| EP-2319923-A1 | PYRIPYROPENE A BIOSYNTHETIC GENE | Meiji Seika Kaisha, Ltd. (JP) | 2011-05-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11571400-B2 | ACAT1 inhibitors for treating cancer | ACAT2, ACAT1, CEPT1 | SOAT2 384/4885SOAT1 149/4885 |
| US-11911469-B2 | Combination of ACAT1 inhibitor and checkpoint antibody for treating cancer | CD274, PDCD1, PDCD4 | SOAT2 3131/4885SOAT1 1835/4885 |
| US-10278962-B2 | Tricyclic analogues, preparation method and uses thereof | ACAT2, ACAT1, LCAT | SOAT2 19/4885SOAT1 24/4885 |
| US-20120015410-A1 | PYRIPYROPENE A BIOSYNTHETIC GENE | PNKP, COASY, FDPS | SOAT2 2495/4885SOAT1 2684/4885 |
| US-12605359-B2 | Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor and pharmaceutical use therefor | PCSK9, PCSK7, PCSK6 | SOAT2 393/4885SOAT1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.