Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468470 | 0.80 | GAA (0.31) | LMNAGAAPKMSMN1; SMN2HTT | |
| SCHEMBL12468482 | 0.76 | — | — | |
| SCHEMBL2041571 | 0.68 | KDM4E (0.42) | GAASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL11280178 | 0.67 | MAPT (0.35) | LMNAGAAPKMSMN1; SMN2MEN1 | |
| SCHEMBL11279009 | 0.67 | MAPK1 (0.39) | LMNAGAAPKMSMN1; SMN2MAPT | |
| SCHEMBL12619945 | 0.65 | SMN1; SMN2 (0.48) | LMNAGAAPKMSMN1; SMN2MEN1 | |
| SCHEMBL12377098 | 0.63 | SOAT1 (0.33) | SMN1; SMN2 | |
| SCHEMBL28919941 | 0.62 | ALDH1A1 (0.39) | LMNAGAAPKMSMN1; SMN2MEN1 | |
| SCHEMBL25831015 | 0.60 | MEN1 (0.35) | LMNAPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7032930 | 0.60 | KCNA4 (0.60) | LMNAGAAPKMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012049167-A1 | NOVEL OLIGOTHIOPHENE DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR USES | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2012-04-19 | — | — | WO | disclosed |