Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13202049 | 0.82 | MEN1 (0.33) | MEN1KMT2AHTT | |
| SCHEMBL26290593 | 0.79 | GAA (0.36) | GAAL3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5405789 | 0.78 | KDM4E (0.32) | MEN1KMT2AHTT | |
| SCHEMBL7211170 | 0.77 | MEN1 (0.30) | MEN1KMT2AHTT | |
| SCHEMBL4387071 | 0.77 | MEN1 (0.33) | GAAL3MBTL1MEN1KMT2AHTT | |
| SCHEMBL2025232 | 0.74 | GAA (0.33) | GAAL3MBTL1MEN1KMT2AHTT | |
| SCHEMBL987956 | 0.73 | MEN1 (0.33) | GAAL3MBTL1MEN1KMT2AHTT | |
| SCHEMBL13202053 | 0.71 | MEN1 (0.33) | MEN1KMT2AHTT | |
| SCHEMBL13328964 | 0.71 | GAA (0.35) | GAAL3MBTL1HTT | |
| SCHEMBL18545545 | 0.71 | GAA (0.44) | GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985594-B2 | Biradical polarizing agents for dynamic nuclear polarization | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-07-26 | — | — | US | disclosed |
| US-20090302842-A1 | BIRADICAL POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | MASSACHUSETTS INSTITUTE OF TECNOLOGY (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302842-A1 | BIRADICAL POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | NUMA1, KPNA2, MEN1 | GAA 4396/4885L3MBTL1 2333/4885MEN1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.