SCHEMBL12468674

SCHEMBL12468674

C=CC(=O)OC(CC)[Si](CCCC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
HPGD P15428 1/20 0.41
THRB P10828 2/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
FAAH O00519 1/20 0.31
THRA P10827 1/20 0.31
LMNA P02545 2/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1061254 0.91 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL1068307 0.84 TSHR (0.35) TSHRHPGD
SCHEMBL27979488 0.84 TSHR (0.38) TSHRHPGD
SCHEMBL16537979 0.84 TSHR (0.43) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL28183077 0.83 TSHR (0.34) TSHRHPGD
SCHEMBL6270901 0.81 PRKCA (0.36) LMNACA1CA2ALDH1A1
SCHEMBL16537203 0.80 TSHR (0.36) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL7221819 0.79 TSHR (0.39) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL16537900 0.79 TSHR (0.44) TSHRHPGDTHRBTHRACA1
SCHEMBL6267178 0.78 LMNA (0.42) TSHRLMNAALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP disclosed
EP-3310793-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP disclosed
WO-2016205648-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
WO-2016205642-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
CN-104822788-B Water-dispersed pressure-sensitive adhesive composition, adhesive phase, bonding sheet and comprise the duplexer of this adhesive phase or bonding sheet 日东电工株式会社 2016-09-14 CN disclosed
CN-104371582-B Transparent and electrically conductive film, transparent conductive laminate and touch panel with adhesive phase 日东电工株式会社 2016-08-24 CN disclosed
CN-105722936-A Water-dispersible adhesive composition for optical film, adhesive layer, adhesive optical film, and image display device 日东电工株式会社 2016-06-29 CN disclosed
CN-105637394-A Optical member with adhesive layer, image display device, and method for manufacturing optical member with adhesive layer NITTO DENKO CORP 2016-06-01 CN disclosed
CN-105518097-A Water-dispersible adhesive composition, adhesive layer, adhesive optical film, and image display device NITTO DENKO CORP 2016-04-20 CN disclosed
CN-104334664-B Pressure-sensitive adhesive for optical films layer, with the blooming of binder layer and image display device NITTO DENKO CORP. (JP) 2016-04-13 CN disclosed
CN-103038304-B Pressure-sensitive adhesive layer for transparent conductive film, transparent conductive film with pressure-sensitive adhesive layer, transparent conductive laminate, and touch panel NITTO DENKO CORP 2015-03-25 CN disclosed
CN-104371582-A Pressure-sensitive adhesive layer for transparent conductive film, transparent conductive film with pressure-sensitive adhesive layer, transparent conductive laminate, and touch panel NITTO DENKO CORP 2015-02-25 CN disclosed
CN-102933677-B Pressure-sensitive adhesive composition for optical film, pressure-sensitive adhesive layer for optical film, pressure-sensitive adhesive optical film, and image display device NITTO DENKO CORP 2015-02-25 CN disclosed
CN-104334664-A Adhesive layer for optical films, optical film with adhesive layer, and image display device NITTO DENKO CORP 2015-02-04 CN disclosed
CN-103249497-B Method and apparatus for applying coating solution, and method for manufacturing coated product NITTO DENKO CORP 2015-01-07 CN disclosed
EP-2785726-A2 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS Dow Corning Corporation (US) 2014-10-08 EP disclosed
EP-2762482-A1 Process for purifying an acryloyloxysilane Dow Corning Corporation (US) 2014-08-06 EP disclosed
EP-2621936-A2 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2013-08-07 EP disclosed
WO-2013081820-A2 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS DOW CORNING CORPORATION (US) 2013-06-06 WO disclosed
WO-2012050761-A2 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2012-04-19 WO disclosed