SCHEMBL6267178

SCHEMBL6267178

CCCC[Si](OC)(OC)C(CC)OC(=O)CCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.42
MAPK1 P28482 3/20 0.40
MAPT P10636 2/20 0.40
ALDH1A1 P00352 2/20 0.38
PRKCA P17252 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCD Q05655 1/20 0.36
TSHR P16473 2/20 0.35
CYP3A4 P08684 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 3/20 0.34
EPHX2 P34913 1/20 0.34
MEN1 O00255 1/20 0.33
GMNN O75496 1/20 0.33
HSP90AA1 P07900 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6270901 0.83 PRKCA (0.36) LMNAMAPK1MAPTALDH1A1PRKCA
SCHEMBL6271670 0.78 ALDH1A1 (0.41) LMNAMAPK1MAPTALDH1A1PRKCA
SCHEMBL28451842 0.76 LMNA (0.40) LMNAMAPK1MAPTALDH1A1
SCHEMBL6267472 0.76 LMNA (0.40) LMNAMAPK1MAPTALDH1A1
SCHEMBL8839454 0.75 LMNA (0.56) LMNAMAPK1MAPTALDH1A1PRKCA
SCHEMBL8839357 0.75 LMNA (0.56) LMNAMAPK1MAPTALDH1A1PRKCA
SCHEMBL6559391 0.75 LMNA (0.56) LMNAMAPK1MAPTALDH1A1PRKCA
SCHEMBL8839277 0.75 LMNA (0.56) LMNAMAPK1MAPTALDH1A1PRKCA
SCHEMBL8839316 0.75 LMNA (0.46) LMNAMAPK1MAPTALDH1A1PRKCA
SCHEMBL3226362 0.72 ALDH1A1 (0.43) LMNAMAPK1MAPTALDH1A1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005103061-A1 METHOD OF MANUFACTURING AN ORGANOALKOXYSILANE HAVING ESTER-FUNCTIONAL GROUPS DOW CORNING TORAY CO., LTD. (JP) 2005-11-03 WO disclosed