SCHEMBL6270901

SCHEMBL6270901

CCCC[Si](OC)(OC)C(CC)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.36
ALDH1A1 P00352 1/20 0.34
LMNA P02545 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267178 0.83 LMNA (0.42) PRKCAALDH1A1LMNAMAPTMAPK1
SCHEMBL12468674 0.81 TSHR (0.41) ALDH1A1LMNACA1CA2
SCHEMBL82327 0.74 TSHR (0.37) ALDH1A1LMNAMAPT
SCHEMBL28529148 0.72 TSHR (0.36) ALDH1A1LMNAMAPT
SCHEMBL6267517 0.72 TSHR (0.36) ALDH1A1LMNAMAPT
SCHEMBL4412389 0.72 TSHR (0.36) ALDH1A1LMNAMAPT
SCHEMBL8839330 0.70 ALDH1A1 (0.44) PRKCAALDH1A1LMNACA1CA2
SCHEMBL2751669 0.70 ZDHHC7 (0.40) PRKCAALDH1A1CA1MAPT
SCHEMBL1061254 0.70 TSHR (0.36)
SCHEMBL28489600 0.68 ALDH1A1 (0.32) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005103061-A1 METHOD OF MANUFACTURING AN ORGANOALKOXYSILANE HAVING ESTER-FUNCTIONAL GROUPS DOW CORNING TORAY CO., LTD. (JP) 2005-11-03 WO disclosed