SCHEMBL12468706

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5035158	0.85	MAPT (0.73)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL19371462	0.82	L3MBTL1 (1.00)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL23084203	0.81	EPHX2 (0.62)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL9070653	0.81	EPHX2 (0.73)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL23084237	0.79	MAPT (0.59)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL18031171	0.79	MAPT (0.86)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL14386321	0.78	LMNA (1.00)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL22816430	0.77	EPHX2 (0.67)	MAPTL3MBTL1EPHX2SMN1; SMN2TRPV1
	SCHEMBL27424887	0.77	MAPT (0.57)	MAPTL3MBTL1KDM4ELMNAEPHX2
	SCHEMBL11555827	0.77	EPHX2 (1.00)	MAPTEPHX2ALDH1A1TRPV1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.