SCHEMBL12469406

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17339081	0.78	KMT2A (0.50)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL29533984	0.78	KMT2A (0.50)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL3802120	0.77	KMT2A (0.56)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL21534086	0.77	KMT2A (0.56)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL10103705	0.76	KMT2A (0.76)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL15347887	0.76	L3MBTL1 (0.41)	KMT2AKDM4EALDH1A1HPGDL3MBTL1
	SCHEMBL16559906	0.76	METAP2 (0.49)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL22004356	0.74	KMT2A (0.53)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL29933328	0.72	KMT2A (0.69)	KMT2AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL11663451	0.72	KMT2A (0.69)	KMT2AMAPTKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.