Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 11/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469427 | 0.82 | BTK (0.67) | FLT3BTKCSF1R | |
| SCHEMBL12469667 | 0.82 | BTK (0.43) | FLT3BTK | |
| SCHEMBL12469863 | 0.79 | BTK (0.42) | FLT3BTK | |
| SCHEMBL12469435 | 0.79 | BTK (0.45) | FLT3BTKCSF1R | |
| SCHEMBL12469700 | 0.78 | BTK (0.40) | FLT3BTK | |
| SCHEMBL12469665 | 0.77 | BTK (0.46) | FLT3BTKCSF1R | |
| SCHEMBL12469189 | 0.77 | BTK (0.46) | FLT3BTKCSF1R | |
| SCHEMBL12469532 | 0.77 | BTK (0.42) | FLT3BTKCSF1R | |
| SCHEMBL12469647 | 0.76 | BTK (0.38) | FLT3BTK | |
| SCHEMBL12469585 | 0.76 | BTK (0.45) | FLT3BTKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |