Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469609 | 0.82 | BTK (0.39) | BTKFLT3PDE3BPDE3AGRM2 | |
| SCHEMBL12469667 | 0.81 | BTK (0.43) | BTKFLT3PDE3BPDE3AGRM2 | |
| SCHEMBL12469271 | 0.78 | NISCH (0.43) | BTKGRM2 | |
| SCHEMBL12469700 | 0.77 | BTK (0.40) | BTKFLT3PDE3BPDE3AGRM5 | |
| SCHEMBL12469593 | 0.77 | BTK (0.44) | BTKPDE3BPDE3AGRM5GRM2 | |
| SCHEMBL12469863 | 0.76 | BTK (0.42) | BTKFLT3PDE3BPDE3AGRM2 | |
| SCHEMBL12469435 | 0.76 | BTK (0.45) | BTKFLT3PDE3BPDE3AGRM2 | |
| SCHEMBL12469516 | 0.76 | GRM2 (0.40) | BTKFLT3PDE3BPDE3AGRM5 | |
| SCHEMBL12469765 | 0.76 | AURKA (0.40) | BTKFLT3GRM5GRM2 | |
| SCHEMBL12469688 | 0.76 | FLT3 (0.48) | BTKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |