SCHEMBL12469733

SCHEMBL12469733

O=P(O)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F.[MgH2]

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 3/20 0.43
PGK2 P07205 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL186903 0.97 PGK1 (0.45) PGK1PGK2
SCHEMBL15136324 0.93 PGK1 (0.43) PGK1PGK2
Ammonia Solution, Strong SCHEMBL6471811 0.93 PGK1 (0.43) PGK1PGK2
SCHEMBL4017894 0.93 PGK1 (0.43) PGK1PGK2
SCHEMBL13493664 0.83 PGK1 (0.42) PGK1PGK2
Isopropylamine SCHEMBL6047054 0.81 LAP3 (0.39) PGK1PGK2
SCHEMBL13493660 0.79 PGK1 (0.43) PGK1PGK2
SCHEMBL13493687 0.79 PGK1 (0.39) PGK1PGK2
SCHEMBL1541929 0.78 PGK1 (0.41) PGK1PGK2
SCHEMBL3272287 0.77 FDPS (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621939-B1 FUNCTIONALIZED FLUOROALKYL FLUOROPHOSPHATE SALTS MERCK PATENT GMBH (DE) 2015-06-10 EP disclosed
US-8846922-B2 Functionalized fluoroalkyl fluorophosphate salts MERCK PATENT GMBH (DE) 2014-09-30 US disclosed
EP-2621939-A1 FUNCTIONALIZED FLUOROALKYL FLUOROPHOSPHATE SALTS Merck Patent GmbH (DE) 2013-08-07 EP disclosed
US-20130197228-A1 FUNCTIONALIZED FLUOROALKYL FLUOROPHOSPHATE SALTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-08-01 US disclosed
WO-2012048772-A1 FUNCTIONALIZED FLUOROALKYL FLUOROPHOSPHATE SALTS MERCK PATENT GMBH (DE) 2012-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130197228-A1 FUNCTIONALIZED FLUOROALKYL FLUOROPHOSPHATE SALTS INPPL1, INPP5D, PLCB3 PGK1 3367/4885PGK2 3076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.