SCHEMBL1541929

SCHEMBL1541929

O=P(O)(C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 3/20 0.41
PGK2 P07205 3/20 0.41
THRB P10828 1/20 0.32
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1542142 0.91 PGK1 (0.39) PGK1PGK2THRBKDM4ETSHR
SCHEMBL6656608 0.88 THRB (0.40) PGK1PGK2THRB
SCHEMBL26087767 0.88 THRB (0.40) PGK1PGK2THRB
SCHEMBL232318 0.88 THRB (0.40) PGK1PGK2THRB
SCHEMBL13493709 0.87 PGK1 (0.39) PGK1PGK2
SCHEMBL13493630 0.87 PGK1 (0.39) PGK1PGK2
SCHEMBL13493659 0.84 PGK1 (0.40) PGK1PGK2
SCHEMBL1541142 0.81 PGK1 (0.55) PGK1PGK2THRBKDM4ETSHR
SCHEMBL7095111 0.80 PGK1 (0.36) PGK1PGK2
SCHEMBL7092374 0.80 PGK1 (0.36) PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1495035-B1 METHOD FOR THE PRODUCTION OF BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS AND THE SALTS THEREOF MERCK PATENT GMBH (DE) 2010-06-30 EP claimed
EP-4389754-A1 METAL-ORGANIC COORDINATION COMPOUND AND METHOD FOR PRODUCING THE SAME beeOLED GmbH (DE) 2024-06-26 EP disclosed
EP-2820026-B1 PROCESS FOR PRODUCING PHOSPHINIC ACID ESTERS MERCK PATENT GMBH (DE) 2016-01-13 EP disclosed
US-9056881-B2 Process for the preparation of phosphinic acid esters MERCK PATENT GMBH (DE) 2015-06-16 US disclosed
US-20150045572-A1 PROCESS FOR THE PREPARATION OF PHOSPHINIC ACID ESTERS MERCK PATENT GMBH (DE) 2015-02-12 US disclosed
EP-2820026-A1 PROCESS FOR PRODUCING PHOSPHINIC ACID ESTERS Merck Patent GmbH (DE) 2015-01-07 EP disclosed
EP-2303899-B1 PROCESS FOR PREPARING BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID MERCK PATENT GMBH (DE) 2014-09-24 EP disclosed
WO-2013127493-A1 PROCESS FOR PRODUCING PHOSPHINIC ACID ESTERS MERCK PATENT GMBH (DE) 2013-09-06 WO disclosed
US-20110130589-A1 PROCESS FOR THE PREPARATION OF BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-06-02 US disclosed
EP-2303899-A1 PROCESS FOR PREPARING BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID Merck Patent GmbH (DE) 2011-04-06 EP disclosed
EP-1685095-B1 METHOD FOR THE PRODUCTION OF ORGANIC SALTS CONTAINING BIS(PERFLUOROALKYL)PHOSPHINATE ANIONS MERCK PATENT GMBH (DE) 2010-08-11 EP disclosed
WO-2010012359-A1 PROCESS FOR PREPARING BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID MERCK PATENT GMBH (DE) 2010-02-04 WO disclosed
US-7576242-B2 N-Ethylpyridinium bis(pentafluoroethyl)phosphinate; reacting tris(perfluoroalkyl)phosphine oxide is reacted with an alcohol and an organic base; ionic liquids MERCK PATENT GMBH (DE) 2009-08-18 US disclosed
US-20070128515-A1 Process for the preparation of organic salts containing bis(perfluoroalkyl) phosphinate anions MERCK PATENT GMBH (DE) 2007-06-07 US disclosed
EP-1685095-A1 METHOD FOR THE PRODUCTION OF ORGANIC SALTS CONTAINING BIS(PERFLUOROALKYL)PHOSPHINATE ANIONS MERCK PATENT GmbH (DE) 2006-08-02 EP disclosed
WO-2005049555-A1 METHOD FOR THE PRODUCTION OF ORGANIC SALTS CONTAINING BIS(PERFLUOROALKYL)PHOSPHINATE ANIONS MERCK PATENT GMBH (DE) 2005-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130589-A1 PROCESS FOR THE PREPARATION OF BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID PHOSPHO1, PPIP5K2, PTEN PGK1 784/4885PGK2 1141/4885THRB 1568/4885
US-20150045572-A1 PROCESS FOR THE PREPARATION OF PHOSPHINIC ACID ESTERS PHOSPHO1, ALK, PTEN PGK1 395/4885PGK2 443/4885THRB 2716/4885
US-20070128515-A1 Process for the preparation of organic salts containing bis(perfluoroalkyl) phosphinate anions PHOSPHO1, PFAS, PFKFB1 PGK1 563/4885PGK2 656/4885THRB 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.