Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 3/20 | 0.40 |
| ▸ | CBFB | Q13951 | 3/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408832 | 0.79 | NPC1 (0.59) | IRAK4NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL983700 | 0.77 | MAPT (0.61) | NPC1RAB9APDK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2906176 | 0.76 | MAPT (0.59) | NPC1RAB9APDK1ALDH1A1HPGD | |
| SCHEMBL13310867 | 0.73 | PDK1 (0.58) | NPC1RAB9APDK1ALDH1A1HPGD | |
| SCHEMBL28211490 | 0.73 | HSP90AA1 (0.51) | IRAK4ALDH1A1KDM4EDHFRTSHR | |
| SCHEMBL11646035 | 0.72 | POLB (0.57) | NPC1RAB9APDK1ALDH1A1HPGD | |
| SCHEMBL13523005 | 0.71 | RAB9A (0.52) | IRAK4NPC1RAB9APDK1ALDH1A1 | |
| SCHEMBL7258252 | 0.71 | SMN1; SMN2 (0.47) | IRAK4NPC1RAB9APDK1ALDH1A1 | |
| SCHEMBL2928530 | 0.71 | NPC1 (0.49) | NPC1RAB9APDK1ALDH1A1HPGD | |
| SCHEMBL13998719 | 0.71 | NPC1 (0.49) | NPC1RAB9APDK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |