Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248454 | 0.85 | — | — | |
| Bicarbonate SCHEMBL27799736 | 0.83 | PHF8 (0.48) | PHF8KDM2AKDM7ALMNASLC22A6 | |
| SCHEMBL9816328 | 0.80 | LMNA (0.40) | PHF8KDM2AKDM7ALMNASLC22A6 | |
| Behenic Acid SCHEMBL28853506 | 0.80 | GPR84 (0.63) | LMNASLC22A6TSHRAKR1B1PPARG | |
| Stearic Acid SCHEMBL1338062 | 0.80 | GPR84 (0.63) | LMNASLC22A6TSHRAKR1B1PPARG | |
| SCHEMBL20239066 | 0.74 | LMNA (0.43) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Glutarate SCHEMBL5874412 | 0.73 | SLC22A6 (0.73) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL5874870 | 0.73 | LMNA (0.73) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL5874879 | 0.73 | LMNA (0.73) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Glutarate SCHEMBL5874406 | 0.73 | SLC22A6 (0.73) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282989-B1 | PROCESS FOR PREPARING 3-(2,2-DIMETHYLHYDRAZINO)METHYLPROPIONATE | GRINDEKS JSC (LV) | 2011-10-12 | — | — | EP | claimed |
| EP-2282989-A1 | PROCESS FOR PREPARING 3-(2,2-DIMETHYLHYDRAZINO)METHYLPROPIONATE | Grindeks, a joint stock company (LV) | 2011-02-16 | — | — | EP | claimed |
| WO-2009144221-A1 | PROCESS FOR PREPARING 3-(2,2- DIMETHYLHYDRAZINO) METHYLPROPIONATE | GRINDEKS, A JOINT STOCK COMPANY (LV) | 2009-12-03 | — | — | WO | claimed |
| CN-104165965-B | Analysis method for non-aqueous titration determination of content of mildronate bulk drug intermediate methyl 3- (2, 2-dimethylhydrazino) propionate | 东力（南通）化工有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-104165965-B | Analysis method for non-aqueous titration determination of content of mildronate bulk drug intermediate methyl 3- (2, 2-dimethylhydrazino) propionate | 东力（南通）化工有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-104165965-A | Analysis method for non-aqueous titration determination of content of mildronate bulk drug intermediate methyl 3- (2, 2-dimethylhydrazino) propionate | DONGLI NANTONG CHEMICALS CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-104163776-A | Improved preparation technology method of 3- (2, 2-dimethylhydrazino) methyl propionate and 3- (2,2, 2-trimethylhydrazine) methyl propionate | DONGLI NANTONG CHEMICALS CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-104163776-A | Improved preparation technology method of 3- (2, 2-dimethylhydrazino) methyl propionate and 3- (2,2, 2-trimethylhydrazine) methyl propionate | DONGLI NANTONG CHEMICALS CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-104163776-A | Improved preparation technology method of 3- (2, 2-dimethylhydrazino) methyl propionate and 3- (2,2, 2-trimethylhydrazine) methyl propionate | DONGLI NANTONG CHEMICALS CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-104165965-A | Analysis method for non-aqueous titration determination of content of mildronate bulk drug intermediate methyl 3- (2, 2-dimethylhydrazino) propionate | DONGLI NANTONG CHEMICALS CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-104151192-A | Improved method of mildronate intermediate 3- (2,2, 2-trimethylhydrazinium) methyl propionate methyl sulfate preparation technology | DONGLI NANTONG CHEMICALS CO LTD | 2014-11-19 | — | — | CN | disclosed |
| EP-2282989-B1 | PROCESS FOR PREPARING 3-(2,2-DIMETHYLHYDRAZINO)METHYLPROPIONATE | GRINDEKS JSC (LV) | 2011-10-12 | — | — | EP | disclosed |
| CN-102036949-A | Preparation method of 3- (2, 2-dimethylhydrazino) methyl propionate | GRINDEKS JSC | 2011-04-27 | — | — | CN | disclosed |
| CN-102036949-A | Preparation method of 3- (2, 2-dimethylhydrazino) methyl propionate | GRINDEKS JSC | 2011-04-27 | — | — | CN | disclosed |
| EP-2282989-A1 | PROCESS FOR PREPARING 3-(2,2-DIMETHYLHYDRAZINO)METHYLPROPIONATE | Grindeks, a joint stock company (LV) | 2011-02-16 | — | — | EP | disclosed |
| EP-2282989-A1 | PROCESS FOR PREPARING 3-(2,2-DIMETHYLHYDRAZINO)METHYLPROPIONATE | Grindeks, a joint stock company (LV) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009144221-A1 | PROCESS FOR PREPARING 3-(2,2- DIMETHYLHYDRAZINO) METHYLPROPIONATE | GRINDEKS, A JOINT STOCK COMPANY (LV) | 2009-12-03 | — | — | WO | disclosed |
| EP-2128126-A1 | New process for the preparation of 3-(2,2,2-Trimethylhydrazinium) propionate dihydrate | Grindeks, a joint stock company (LV) | 2009-12-02 | — | — | EP | disclosed |
| US-4704403-A | HYPOTENSIVE, ANTIARRHYTHMIA | BREMANIS GUNAR A (SU) | 1987-11-03 | — | — | US | disclosed |
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |